The clinical course of the disease, myocardial functional status and blood rheological properties were examined in coronary heart disease patients with postinfarction and angiographically evidenced intact coronary arteries. This group of patients was shown to be characterized by young age, acute onset of the disease and rather favourable prognosis. The abnormalities were caused by extended postinfarction asynergies, yet there was no significant progression of circulatory insufficiency even in patients with left ventricular aneurysm during a long-term follow-up (5.2 +/- 0.2 years). A correlation was found between the level of myocardial blood flow and the degree of disturbed blood rheological properties. It is suggested that impaired blood rheology along with altered coronary tone should determine the functional component of coronary resistance and represent a main mechanism of coronary insufficiency in patients with coronary heart disease and unchanged coronary arteries, as evidenced by angiography.
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