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The polysaccharide fractions were obtained from flower buds of the four substitutes of Lonicera japonica, L. macranthoides (LMPB), L. hypoglauca (LHPB), L.

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Hyperglycemia and dyslipidemia are classic features for diabetes mellitus (DM). In this study, one fraction of the crude polysaccharides extracted from Lonicera japonica flower buds (LJP) were investigated for its hypolipidaemic and hypoglycaemic activities by means of streptozotocin (STZ)-induced diabetic rats. Interestingly, after orally administrated with 800mg/kg body weight (B.

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[The effects of aerobic exercise on ERK1/2 activity in skeletal muscle of type 2 diabetic rats].

Zhongguo Ying Yong Sheng Li Xue Za Zhi

January 2017

School of Sports Science, Shenyang Sport University, Shenyang 110102, China.

Objective: To observe the effects of aerobic exercise on activity of extracellular signal-regulated kinase (ERK1/2) in skeletal muscle of type 2 diabetic rats and explore the prevention and control mechanism of aerobic exercise on type 2 diabetes.

Methods: Seventy five SD rats were randomly divided into:normal control group(CON) including 15 rats was fed with normal diet, diabetes control group 1(DC1), diabetes exercise group 1(DE1), diabetes control group 2(DC2), diabetes exercise group 2(DE2). Diabetes model group were fed with high-fatty and high-sugar diet.

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In this study, cholesterin was implanted in the subcutaneous tissue in mice to induce the formation of cholesterol granuloma. Histological examination was carried out to determine the type and source of cells. The tissue surrounding the embedded cholesterin was examined histologically within the period of 6 months.

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Objective: This study was designed to investigate the effects of metformin on bile acid in type 2 diabetes mellitus (T2DM).

Methods: In this study, we constructed a model of T2DM by a combination of high-fat diet (HFD) and low dose of streptozotocin (STZ) intraperitoneal injection. Blood samples by tail vein and eye angular vein were withdrawn before (time 0) and 30, 60, and 120 minutes after administration of glucose before STZ injection and once a week after diabetes induction, and were analyzed to evaluate the level of the fasting blood glucose and fasting insulin using glucometer.

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