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Short Course of Systemic Steroids for Acute Respiratory Diseases During Infancy and Final Adult Height, Weight, and BMI: Preliminary Results from a Prospective Cohort Study.
J Clin Med
January 2025
Laboratory of Research of the Musculosceletal System, National and Kapodistrian University of Athens, KAT General Hospital, 14561 Athens, Greece.
Systemic corticosteroids are frequently used to manage acute respiratory diseases in infancy, but concerns about the long-term impacts on growth remain. This study aimed to evaluate the impact of short courses of systemic steroids administered exclusively during infancy on final adult height, weight, and BMI, adjusted by sex and cumulative steroid use. : A prospective cohort study was conducted including 257 participants (49.
View Article and Find Full Text PDFNovel Intravenous Nanoemulsions Based on Cannabidiol-Enriched Hemp Oil-Development and Validation of an HPLC-DAD Method for Cannabidiol Determination.
Molecules
January 2025
Chair and Department of Pharmaceutical Chemistry, Poznan University of Medical Sciences, Rokietnicka 3, 60-806 Poznan, Poland.
Background: Intravenous nanoemulsions (NEs) are gaining attention as potential delivery systems for poorly water-soluble substances like cannabidiol (CBD). This study aimed to develop novel NEs based on CBD-enriched hemp oils and evaluate their physiochemical properties.
Methods: The stability of hemp oils enriched with various concentrations of CBD (0.
Benefits of Immobilized Bacteria in Bioremediation of Sites Contaminated with Toxic Organic Compounds.
Microorganisms
January 2025
Department of Molecular Environmental Biotechnology, Helmholtz Centre for Environmental Research-UFZ, 04318 Leipzig, Germany.
Although bioremediation is considered the most environmentally friendly and sustainable technique for remediating contaminated soil and water, it is most effective when combined with physicochemical methods, which allow for the preliminary removal of large quantities of pollutants. This allows microorganisms to efficiently eliminate the remaining contaminants. In addition to requiring the necessary genes and degradation pathways for specific substrates, as well as tolerance to adverse environmental conditions, microorganisms may perform below expectations.
View Article and Find Full Text PDFThyme Essential Oil as a Potential Tool Against Common and Re-Emerging Foodborne Pathogens: Biocidal Effect on Bacterial Membrane Permeability.
Microorganisms
December 2024
Department of Molecular Medicine and Medical Biotechnologies, University of Naples "Federico II", 80131 Naples, Italy.
Over the past decade, foodborne diseases have become a significant public health concern, affecting millions of people globally. Major pathogens like spp., , , and contaminate food and cause several infections.
View Article and Find Full Text PDFThe Role of ChatGPT and AI Chatbots in Optimizing Antibiotic Therapy: A Comprehensive Narrative Review.
Antibiotics (Basel)
January 2025
Faculty of Medicine, University of Medicine and Pharmacy Carol Davila Bucharest, 050474 Bucharest, Romania.
Antimicrobial resistance represents a growing global health crisis, demanding innovative approaches to improve antibiotic stewardship. Artificial intelligence (AI) chatbots based on large language models have shown potential as tools to support clinicians, especially non-specialists, in optimizing antibiotic therapy. This review aims to synthesize current evidence on the capabilities, limitations, and future directions for AI chatbots in enhancing antibiotic selection and patient outcomes.
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