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Clinical characteristics of Japanese patients with severe hypertriglyceridemia.
J Clin Lipidol
May 2016
Division of Cardiovascular Medicine, Kanazawa University Graduate School of Medicine, Kanazawa, Japan.
Background: Although of interest, few data exist on the clinical characteristics of Japanese patients with an extremely high triglyceride level (≥ 1000 mg/dL).
Objective: We assessed the clinical characteristics of Japanese patients with an extremely high triglyceride level.
Methods: We investigated the presence of coronary artery disease, history of pancreatitis, the presence of fatty liver, and the potential causes of elevated triglyceride in Japanese subjects with an extremely high level of fasting triglyceride (≥ 1000 mg/dL) among 70,368 subjects whose serum triglyceride was measured for any reason at Kanazawa University Hospital from April 2004 to March 2014.
PROP-1 gene mutations in a 63-year-old woman presenting with osteoporosis and hyperlipidaemia.
Hormones (Athens)
November 2013
Department of Endocrinology, University Hospital of Ioannina, Ioannina, Greece.
PROP-1 gene mutations have been reported as a cause of combined pituitary hormone deficiency. Physical and hormonal phenotypes of affected individuals are variable. We report a 63-year-old female who presented with osteoporosis.
View Article and Find Full Text PDFAcute pancreatitis in a girl with panhypopituitarism due to craniopharyngioma on growth hormone treatment. A combination of risk factors.
Horm Res
September 2009
Department of Biomedicine of Developmental Age, University of Bari, Bari, Italy.
Craniopharyngioma is a rare, benign, suprasellar brain tumor associated with a significant number of endocrine and metabolic impairments. Growth hormone deficiency, caused by the tumor itself or by its subsequent surgical treatment, is the most common hormone deficiency in these patients and replacement is frequently necessary. Hypothalamic obesity observed after surgery treatment, whether combined with radiotherapy or not, presents with increased abdominal fat and altered lipid profiles and is likely caused by both disruption of the mechanisms controlling satiety, hunger and energy balance and impairment of sensitivity to leptin, insulin and ghrelin axis.
View Article and Find Full Text PDFA case of glomerular lipidosis accompanied by familial combined hyperlipidemia and panhypopituitarism.
Intern Med
January 1992
Department of Medicine, Iwamizawa Municipal General Hospital, Japan.
This is a report of a case of glomerular lipidosis with familial combined hyperlipidemia and panhypopituitarism. A 60-yr-old woman was admitted for evaluation of hyponatremia. Administration of hydrocortisone normalized the level of serum Na.
View Article and Find Full Text PDFSuccessful treatment of primary sterility in a woman having the rare association of panhypopituitarism with Fredrickson's Type V hyperlipemia is described. Replacement therapy with l-thyroxine, prednisone and a low fat diet cleared the patient's blood of the excessive chylomicrons and very low density lipoproteins. Ovulation was induced with human gonadotrophins, and triplets (two normal girls and a boy) were born.
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