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Dormancy: Waiting for Insurgency.
Curr Pharm Biotechnol
July 2023
Department of Bacteriology and Virology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Relapse infection usually results from resistance to the antibiotic, acquired genes, or persister cells. Persister cells are formed through mutation, reduced activity or metabolically inactive pathways induced by antibiotics, harassing conditions, low ATP, and malnutrition. These factors provide the ground for bacteria to grow slowly.
View Article and Find Full Text PDFThe Effect of Long-Term Storage on .
Pol J Microbiol
September 2021
Polissya National University, Faculty of Veterinary Medicine, Zhytomyr, Ukraine.
It was established that when stored for many years (10-13 years) in low-temperature conditions (3°C), without sub-culture on a nutrient medium, grew as visible colonies along the line of inoculation. However, due to long-term storage in conditions of low temperature (3°C) morphology of mycobacteria differed significantly from initial cultures formed by rod-shaped bacteria. Some of them became pigment-forming and smooth on the surface.
View Article and Find Full Text PDFStudy on antibiotic susceptibility of Salmonella typhimurium L forms to the third and forth generation cephalosporins.
Sci Rep
February 2020
Department of Microbiology, Bengbu Medical College, Bengbu, Anhui, 233030, P.R. China.
Salmonella typhimurium is a pathogenic gram-negative bacterium, which is found primarily in the intestinal lumen. It often causes diarrhea in infants and young children and leads to food poisoning. Drug resistance of Salmonella typhimurium presented serious complications in clinical patients.
View Article and Find Full Text PDFUnusual features and molecular pathways of Staphylococcus aureus L-form bacteria.
Microb Pathog
March 2020
Department of Pathogenic Biology, School of Basic Medical Sciences, Lanzhou University, Lanzhou, 730000, China. Electronic address:
Staphylococcus aureus can be converted to cell wall-deficient L-form bacteria in specific environment which is associated with recurrent and persistent infections. The biophysical properties and molecular basis involved in S. aureus L-form formation are poorly understood.
View Article and Find Full Text PDFThe Pseudomonas aeruginosa Complement of Lactate Dehydrogenases Enables Use of d- and l-Lactate and Metabolic Cross-Feeding.
mBio
September 2018
Department of Biological Sciences, Columbia University, New York, New York, USA
is the most common cause of chronic, biofilm-based lung infections in patients with cystic fibrosis (CF). Sputum from patients with CF has been shown to contain oxic and hypoxic subzones as well as millimolar concentrations of lactate. Here, we describe the physiological roles and expression patterns of lactate dehydrogenases in the contexts of different growth regimes.
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