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Value Propositions for Digital Shared Medication Plans to Boost Patient-Health Care Professional Partnerships: Co-Design Study.
J Particip Med
January 2025
Department of Ambulatory Care, Center for Primary Care and Public Health (Unisanté), University of Lausanne, Lausanne, Switzerland.
Background: Health authorities worldwide have invested in digital technologies to establish robust information exchange systems for improving the safety and efficiency of medication management. Nevertheless, inaccurate medication lists and information gaps are common, particularly during care transitions, leading to avoidable harm, inefficiencies, and increased costs. Besides fragmented health care processes, the inconsistent incorporation of patient-driven changes contributes to these problems.
View Article and Find Full Text PDFIntegration of social work into specialist palliative home service.
Palliat Care Soc Pract
January 2025
Heidelberg University Hospital - Department of Palliative Medicine, Germany.
Background: The specialist palliative home service (SAPV) federal framework contract for adults, to be enacted in Germany until 2028, does not legally mandate the hiring of a third professional group beyond specialist nurses and physicians, although palliative care embraces the psychosocial dimension and an interprofessional approach.
Objectives: This article aims to explore the role of medical staff in integrating social work (SW) into SAPV.
Design: Qualitative case study.
Detection of circular permutations by Protein Language Models.
Comput Struct Biotechnol J
December 2024
School of Bioengineering, Qilu University of Technology (Shandong Academy of Sciences), Jinan, Shandong 250300, China.
Protein circular permutations are crucial for understanding protein evolution and functionality. Traditional detection methods face challenges: sequence-based approaches struggle with detecting distant homologs, while structure-based approaches are limited by the need for structure generation and often treat proteins as rigid bodies. Protein Language Model-based alignment tools have shown advantages in utilizing sequence information to overcome the challenges of detecting distant homologs without requiring structural input.
View Article and Find Full Text PDFEmerging Strategies in Cartilage Repair and Joint Preservation.
Medicina (Kaunas)
December 2024
Faculty of Medicine, Victor Babes University of Medicine and Pharmacy, 2 Eftimie Murgu, 300041 Timisoara, Romania.
Cartilage repair remains a critical challenge in orthopaedic medicine due to the tissue's limited self-healing ability, contributing to degenerative joint conditions such as osteoarthritis (OA). In response, regenerative medicine has developed advanced therapeutic strategies, including cell-based therapies, gene editing, and bioengineered scaffolds, to promote cartilage regeneration and restore joint function. This narrative review aims to explore the latest developments in cartilage repair techniques, focusing on mesenchymal stem cell (MSC) therapy, gene-based interventions, and biomaterial innovations.
View Article and Find Full Text PDFExplainable AI in Diagnostic Radiology for Neurological Disorders: A Systematic Review, and What Doctors Think About It.
Diagnostics (Basel)
January 2025
Aerospace Engineering Department and Interdisciplinary Research Center for Smart Mobility and Logistics, and Interdisciplinary Research Center Aviation and Space Exploration, King Fahd University of Petroleum and Minerals, Dhahran 31261, Saudi Arabia.
Artificial intelligence (AI) has recently made unprecedented contributions in every walk of life, but it has not been able to work its way into diagnostic medicine and standard clinical practice yet. Although data scientists, researchers, and medical experts have been working in the direction of designing and developing computer aided diagnosis (CAD) tools to serve as assistants to doctors, their large-scale adoption and integration into the healthcare system still seems far-fetched. Diagnostic radiology is no exception.
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