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Viruses
January 2025
Clinical Center for Biotherapy, Zhongshan Hospital, Fudan University, Shanghai 200433, China.
This study aimed to create a new recombinant virus by modifying the EV-A71 capsid protein, serving as a useful tool and model for studying human Enteroviruses. We developed a new screening method using EV-A71 pseudovirus particles to systematically identify suitable insertion sites and tag types in the VP1 capsid protein. The pseudovirus's infectivity and replication can be assessed by measuring postinfection luciferase signals.
View Article and Find Full Text PDFAm J Sports Med
January 2025
The Steadman Clinic, Vail, Colorado, USA.
Background: There is growing evidence that medial meniscotibial ligament (MTL) deficiency and medial meniscus extrusion may precede the development of some medial meniscus posterior root (MMPR) tears. However, no study has investigated the biomechanical consequences of MTL deficiency on the MMPR.
Hypothesis: (1) MTL deficiency leads to increased medial meniscus extrusion, (2) increased medial meniscus extrusion is correlated with increased compression and shear forces at the MMPR, and (3) MTL repair restores medial meniscus extrusion and MMPR forces to native levels.
Int J Rheum Dis
January 2025
Pediatric Allergy Immunology Unit, Advanced Pediatrics Centre, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Psychiatr Hung
January 2025
Semmelweis Egyetem Pszichiátriai és Pszichoterápiás Klinika, Budapest, Hungary, E-mail:
Who was actually the director of the Department of Neurology and Psychiatry at Balassa Street, for a long time also referred to as the Moravcsik Clinic? A polymath, a genius, or rather a knight of fortune who wanted to draw attention to himself by building a clinic for himself? We looked into this on the occasion of his death anniversary. How did he get from the head of the department to the founding of the Psychiatry and Neurology Clinic? He dreamed up every corner of the Department, which was the most impressive and patient-friendly clinic of its time even in European terms. The building was not only used for the recovery of patients, but also for the continuous medical training of doctors.
View Article and Find Full Text PDFPsychiatr Hung
January 2025
PTE Demográfia és Szociológia Doktori Iskola Addiktológia és Egészségmagatartás Program, Pécs, Hungary, E-mail:
Franco Basaglia's work is the cornerstone of the radical psychiatric movement in Italy. This culminated in the "Basaglia Law" of 1978, which aimed to abolish closed psychiatric institutions. In addition to becoming a symbolic place of movement, Trieste is still trying to preserve and put into practice the Basaglian tradition.
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