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Photothermal-manipulatable shape memory polyacrylamide/gelatin Janus hydrogel with drug carrier array for invasive wound closure and responsive drug release.
Int J Biol Macromol
December 2024
State Key Laboratory of Resource Insects, College of Sericulture, Textile and Biomass Sciences, Southwest University, Chongqing 400715, China. Electronic address:
Traditional wound closure methods often present several issues, including additional puncture wounds, adverse effects from anesthesia, and noticeable scarring. Inspired by embryonic wound healing, a Janus hydrogel (PG/Au-Asp@PCM) is designed to manipulate non-invasive wound closure by photothermal-responsive self-contraction of PG/Au-Asp@PCM, which is attributed to the shape memory behavior of PG/Au-Asp@PCM under near-infrared (NIR). Wherein, gelatin acts as a thermally reversible "switch" and polyacrylamide creates stable and cross-linked "net-points".
View Article and Find Full Text PDFExploring digital health: a qualitative study on adults' experiences with health apps and wearables.
Int J Qual Stud Health Well-being
December 2025
Department of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genova, Genova, Italy.
Purpose: From an active ageing perspective, investigating how adults use apps and wearables for health purposes might improve well-being strategies supported by widely adopted technologies. This study investigated adults' perceptions of using apps and wearables for health purposes.
Methods: A qualitative interview study was conducted.
The effect of KUS121, a novel VCP modulator, against ischemic injury in random pattern flaps.
PLoS One
December 2024
Department of Orthopaedic Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Surgery using skin flaps is essential for soft tissue reconstruction. However, postoperative ischemic injury of the skin flap is a major complication and a top concern after the surgery. Currently, evidence-based drugs to fully prevent ischemic injury are not available.
View Article and Find Full Text PDFImpact of COVID-19 pandemic on surgical training in the United States.
Am J Surg
December 2024
Division of Vascular and Endovascular Surgery, Department of Surgery, Duke University, Durham, NC, USA. Electronic address:
The impact of the coronavirus disease COVID-19 pandemic on surgical training in the United States remains a controversial topic. In this study, we examined resident and fellow operative volumes in the pre-COVID-19 and COVID-19 periods across ten different surgical specialties. Accreditation Council for Graduate Medical Education (ACGME) national data reports were collected for ten surgical specialties, including general surgery, neurological surgery, ophthalmology, orthopedic surgery, pediatric surgery, plastic surgery (independent), thoracic surgery, urology, vascular surgery (integrated), and vascular surgery (traditional).
View Article and Find Full Text PDFAssociation between oxidative balance score and serum cobalt level in population with metal implants: a cross-sectional study from NHANES 2015-2020.
Front Nutr
December 2024
Department of Orthopedics, Fujian Medical University Union Hospital, Fuzhou, Fujian, China.
Background: Growing evidence indicates that metal implants influence the body's oxidative stress status, which in turn affects the degradation and stability of metal implants. The oxidative balance score (OBS) is a composite indicator, reflecting the overall oxidative balance of pro-and antioxidants of the human body. However, the associations between OBS and the level of metal ions on the population with metal implants remain to be elucidated.
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