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| http://dx.doi.org/10.1136/bmj.1.5344.1499 | DOI Listing |
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Due to its simplicity, low cost, safety, and high precision, the fiber displacement interferometer has emerged as a highly promising and feasible method for measuring shock-induced vibrations. However, the harsh environments associated with such shocks pose significant challenges, including the need for resistance to fluctuations in light intensity, immunity to disturbances in the transmission fiber, and the capacity to conduct large-range, high-speed bidirectional measurements. To our knowledge, no existing methods adequately address all these requirements.
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Gluconeogenesis, the reciprocal pathway of glycolysis, is an energy-consuming process that generates glycolytic intermediates from non-carbohydrate sources. In this study, we demonstrate that robust and efficient gluconeogenesis in bacteria relies on the allosteric inactivation of pyruvate kinase, the enzyme responsible for the irreversible final step of glycolysis. Using the model bacterium as an example, we discovered that pyruvate kinase activity is inhibited during gluconeogenesis via its extra C-terminal domain (ECTD), which is essential for autoinhibition and metabolic regulation.
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Pumps in Water Distribution Networks (WDNs) adequately provide effective pressure where low elevation or high head losses are detected within the system. One of the most effective strategies to ensure economic sustainability is Pump Scheduling (PS), assuring the optimization of pump management and enabling significant energy cost saving. Meta-heuristic algorithms can be applied to Pump Scheduling, given their ability to provide reliable global solutions, further complemented by limited computational efforts.
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