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Airway morphology, hyoid position, and serum inflammatory markers of obstructive sleep apnea in children treated with modified twin-block appliances.
BMC Oral Health
January 2025
The First Affiliated Hospital of Chongqing Medical University, No. 1 Youyi Road, Yuzhong District, Chongqing, 400016, P.R. China.
Objective: To investigate the effects of modified twin-block appliances (MTBA) on obstructive sleep apnea (OSA) and mandibular retrognathia and the changes in the upper airway, hyoid bone position, and hypoxia-related inflammatory marker levels in children with OSA.
Methods: This study included children with OSA and mandibular retrognathia and those with class I without mandibular retrognathia (n = 35 each). The experimental group comprised children with OSA and mandibular retrognathia managed using MTBA.
Biparatopic binding of ISB 1442 to CD38 in trans enables increased cell antibody density and increased avidity.
MAbs
December 2025
Ichnos Glenmark Innovation, New York, NY, USA.
ISB 1442 is a bispecific biparatopic antibody in clinical development to treat hematological malignancies. It consists of two adjacent anti-CD38 arms targeting non-overlapping epitopes that preferentially drive binding to tumor cells and a low-affinity anti-CD47 arm to enable avidity-induced blocking of proximal CD47 receptors. We previously reported the pharmacology of ISB 1442, designed to reestablish synthetic immunity in CD38+ hematological malignancies.
View Article and Find Full Text PDFSynergistic effects of and zinc oxide in polyvinyl alcohol films for enhanced UV and blue light shielding, antimicrobial properties, and hydrophobicity: improving application performance in sustainable packaging and protective eyewear.
RSC Adv
January 2025
Research Collaboration Center for Nanocellulose, BRIN-Andalas University Padang 25163 West Sumatera Indonesia.
This study investigates the development and characterization of a novel composite material consisting of polyvinyl alcohol (PVA) integrated with (UG) and zinc oxide (ZnO) as fillers. The synergistic effects of UG and ZnO were investigated, focusing on their ability to enhance the film's properties. UV-vis spectrophotometry demonstrated that the composite film effectively blocked all UV (UV-A and UV-B) and blue light wavelengths.
View Article and Find Full Text PDFScreening of Coulombic Interactions To Achieve a Higher Power Factor in Conjugated Polymers.
ACS Appl Mater Interfaces
January 2025
Institute of Materials Research and Engineering, Agency for Science Technology and Research, 2 Fusionopolis Way, 08-03 Innovis, Singapore 138634, Singapore.
Thermoelectric properties of conducting polymers typically suffer from molecular chain disordering, as charge transport is predominantly controlled by morphology. This is especially more problematic when counterions are introduced to tune the carrier concentration for optimal thermoelectric performance, which disturbs the morphology further. In this work, we introduce a new avenue for enhancing thermoelectric properties without needing to regulate the morphology, namely, by controlling the coulombic interaction between polarons and counterions.
View Article and Find Full Text PDFIntermediate-Term Outcomes and Complications of Ahmed Glaucoma Valve in Type 1 Keratoprostheses.
Cornea
January 2025
VST Centre for Glaucoma Care, L V Prasad Eye Institute, Kallam Anji Reddy Campus, Hyderabad, India.
Purpose: To evaluate intermediate-term outcomes and complications associated with Ahmed glaucoma valve (AGV) implantation in eyes with type 1 keratoprosthesis (KPro).
Methods: We retrospectively reviewed records of 43 eyes of 43 Indian patients with type 1 KPro and AGV from 2009 to 2021 with a minimum of 6-months of follow-up. Five eyes that had AGV before KPro were excluded, leaving 38 eyes for analysis.
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