Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1159/000151779 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Influence of bovine lactoferrin on feeding intolerance and intestinal permeability in preterm infants: a randomized controlled trial.
Eur J Pediatr
November 2024
Faculty of Medicine, Mansoura University, Mansoura, Egypt.
Article Synopsis
- Preterm infants often experience feeding intolerance due to their immature digestive systems, which can lead to increased risks of complications.
- A study was conducted to evaluate the effects of oral bovine lactoferrin (LF) supplementation on feeding intolerance and intestinal health in these infants, using a randomized double-blind design with 60 preterm neonates.
- Results showed that infants receiving lactoferrin achieved full feeding sooner (9 days vs. 15 days) and had lower serum zonulin levels, indicating improved intestinal permeability and feeding tolerance compared to the control group.
Mediterranean Diet Pattern: Potential Impact on the Different Altered Pathways Related to Cardiovascular Risk in Advanced Chronic Kidney Disease.
Nutrients
October 2024
Laboratori Experimental de Nefrologia i Trasplantament (LENIT), Institut d'Investigacions Biomètiques August Pi i Sunyer (IDIBAPS), 08027 Barcelona, Spain.
Background: Cardiovascular disease (CVD) remains the most common cause of mortality in chronic kidney disease (CKD) patients. Several studies suggest that the Mediterranean diet reduces the risk of CVD due to its influence on endothelial function, inflammation, lipid profile, and blood pressure. Integrating metabolomic and proteomic analyses of CKD could provide insights into the pathways involved in uremia-induced CVD and those pathways modifiable by the Mediterranean diet.
View Article and Find Full Text PDFDeficiency of the Hemoglobin-Haptoglobin Receptor, CD163, Worsens Insulin Sensitivity in Obese Male Mice.
Diabetes
December 2024
Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, TN.
Excessive iron accumulation in metabolic organs such as the adipose tissue, liver, and skeletal muscle is associated with increased diabetes risk. Tissue-resident macrophages serve multiple roles, including managing inflammatory tone and regulating parenchymal iron homeostasis, thus protecting against metabolic dysfunction upon iron overload. The scavenger receptor CD163 is uniquely present on tissue-resident macrophages and plays a significant role in iron homeostasis by clearing extracellular hemoglobin-haptoglobin complexes, thereby limiting oxidative damage caused by free hemoglobin in metabolic tissues.
View Article and Find Full Text PDFDiscovery of Biomarkers of a Recombinant Human Erythropoietin Administration to Thoroughbred Geldings by Label-Free Proteomics.
Drug Test Anal
September 2024
Racing Laboratory, The Hong Kong Jockey Club, Sha Tin Racecourse, Sha Tin, Hong Kong, China.
Erythropoiesis-stimulating agents (ESAs) continue to be a significant threat to the integrity of human and equine sports. Besides conventional direct testing, monitoring the biomarkers associated with the effects of ESAs may provide a complementary approach via indirect detection to enhance doping control. In this study, we applied label-free proteomics to discover plasma protein biomarkers in Thoroughbred geldings after administration with a long-acting form of recombinant human erythropoietin (rhEPO), methoxy polyethylene glycol epoetin beta, Mircera.
View Article and Find Full Text PDFAcute-phase proteins as indicators of disease severity and mortality in COVID-19 patients.
Sci Rep
September 2024
Department of Pediatric Laboratory Diagnostics, Medical University of Bialystok, Bialystok, Poland.
The aim of the study was to conduct of relationship of acute-phase proteins (APPs) with the severity of COVID-19 defined by National Institutes of Health and according to the criteria of MEWS scale, with the presence of a cytokine storm, oxygen therapy and patient survival. We enrolled 96 patients with COVID-19 and 30 healthy people. The samples were taken on the day of admission and after 9 days on average.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!