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Introduction: Comorbidities are common among older people, and during the last decade, a strong association between heart failure (HF) and cognitive impairment has been found. As much as 40-50% of individuals with HF will also have some degree of cognitive impairment. Previous studies report an undertreatment for some cardiovascular diseases in patients with major neurocognitive disorder (NCD).

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Article Synopsis
  • - Nonparoxysmal junctional tachycardia with Wenckebach exit block is usually linked to digitalis toxicity.
  • - This report highlights a case where the arrhythmia appeared without the use of digitalis medication.
  • - The patient in this case had underlying structural heart disease, suggesting that other factors may trigger this type of arrhythmia.
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Non‑obstructive mesenteric ischaemia during drug therapy for maxillary cancer: A case report.

Biomed Rep

December 2024

Department of Oral and Maxillofacial Surgery, Faculty of Medicine, Academic Assembly, University of Toyama, Toyama 930-0194, Japan.

Non-occlusive mesenteric ischaemia (NOMI) refers to irreversible intestinal ischaemia and necrosis in the absence of organic obstruction to the mesenteric blood vessels. In cases of delayed diagnosis, the prognosis is poor and the mortality rate is 58-70%, being the highest among patients with acute mesenteric ischaemia. The risk factors for this disease include heart disease, sepsis, and administration of catecholamines and digitalis; however, there are few reports of its onset during drug therapy for malignant tumours.

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Clinical effect of recombinant human brain natriuretic peptide in the treatment of heart failure in elderly patients.

BMC Cardiovasc Disord

September 2024

Department of Pharmacognosy, Jingxian Hospital, No. 489, Taohuatan Road, Jingchuan Town, Jing County, Xuancheng City, 242500, Anhui Province, China.

Background: Heart failure in elderly individuals poses significant challenges due to the decline in cardiac function associated with aging. This study aimed to investigate the clinical efficacy of recombinant human brain natriuretic peptide (rhBNP) for the treatment of heart failure, especially in elderly patients.

Methods: This was a retrospective case control study of the medical records of 60 elderly patients with heart failure admitted to our hospital between December 2020 and December 2023.

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Loop Diuretics: An Overview of Its History and Evolution.

J Assoc Physicians India

September 2024

Cluster Medical Head, Medical Affairs, Cipla Ltd., Mumbai, Maharashtra, India.

Article Synopsis
  • * Diuretics, used for conditions like hypertension and heart failure, increase water and electrolyte excretion, and their development has evolved since the late 1700s, with a major breakthrough in 1957 when chlorothiazide was introduced.
  • * Loop diuretics, including torsemide, furosemide, and ethacrynic acid, were developed in the 1950s and are powerful treatments for severe fluid overload, but they require careful monitoring due to potential side effects.
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