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Drug-Induced Pulmonary Fibrosis: National Database Analysis.
Biomedicines
November 2024
Pharmacovigilance Center, Information and Methodological Center for Expert Evaluation, Record and Analysis of Circulation of Medical Products Under the Federal Service for Surveillance in Healthcare, 4-1 Slavyanskaya Square, 109074 Moscow, Russia.
Background/objectives: Pulmonary fibrosis (PF) results in a progressive decline of lung function due to scarring. Drugs are among the most common causes of PF. The objective of our study was to reveal the structure of drugs involved in PF development.
View Article and Find Full Text PDFSensory regulation of meal sorting in Aedes aegypti mosquitoes.
Sci Rep
December 2024
Department of Molecular, Cell and Systems Biology, University of California, Riverside, CA, 92521, USA.
Meal sorting in mosquitoes is a phenomenon whereby ingested blood and sugar meals are directed to different destinations in the alimentary canal. We undertake a systematic analysis and show that entry of blood in the midgut is influenced by blood components, temperature, and feeding mode, while sugar solutions are directed to the crop in a dose-dependent manner. Sweet and nutritive sugars, like sucrose and maltose, enter the crop more efficiently compared to non-sweet or non-nutritive sugars.
View Article and Find Full Text PDFThe impact of fellowship training on current practice patterns and the job market: a survey of Fellowship Council graduates.
J Gastrointest Surg
February 2025
University of Pennsylvania School of Medicine, Philadelphia, PA, United States.
Background: General surgery has changed significantly over the last decades, with the need for advanced training and expertise. The Fellowship Council (FC) accredits fellowships that train approximately 200 fellows annually. This study aimed to analyze FC graduates' perceptions of training, current practices, and the job market.
View Article and Find Full Text PDFIntroduction to the Use of Microbial Communities.
Adv Biochem Eng Biotechnol
November 2024
University of Helsinki, Helsinki, Finland.
Microbes are the third major group of biospheric organisms after plants and animals. They are responsible for many natural circulations, including the rotation of elements. They return organic carbon for plants' use and dissolve minerals into organic cycles.
View Article and Find Full Text PDFDirect prion neuroinvasion following inhalation into the nasal cavity.
mSphere
December 2024
Department of Medical Microbiology and Immunology, School of Medicine, Creighton University, Omaha, Nebraska, USA.
Inhalation of prions into the nasal cavity is an efficient route of infection. Following inhalation of infectious prions, animals develop disease with a similar incubation period compared with per os exposure, but with greater efficiency. To identify the reason for this increased efficiency, we identified neural structures that uniquely innervate the nasal cavity and neural structures known to mediate neuroinvasion following oral infection and used immunohistochemistry to determine the temporal and spatial accumulation of prions from hamster tissue sections containing cell bodies and axons at 2-week intervals following prion exposure.
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