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Future Directions in the Management of Classic Congenital Adrenal Hyperplasia Due to 21-Hydroxylase Deficiency.
J Clin Endocrinol Metab
January 2025
Departments of Pharmacology and Internal Medicine, Division of Metabolism, Endocrinology and Diabetes, University of Michigan Medical School, Ann Arbor, MI 48109, USA.
Context: The traditional management of classic congenital adrenal hyperplasia due to 21-hydroxylase deficiency (21OHD) is difficult and often suboptimal.
Objective: To review improvements in the diagnosis and management of 21OHD.
Design: Literature review, synthesis, and authors' experience.
Effect of steroid-soaked throat pack on postoperative throat complications following major oral and maxillofacial surgery.
Natl J Maxillofac Surg
November 2024
Department of Family Dentistry, University of Benin Teaching Hospital, Benin-city, Edo State, Nigeria.
Background: Postoperative throat complications (POTCs) are common and distressing to patients; consensus on their optimum treatment is unclear.
Aim: The aim of the study was to determine the efficacy of a steroid-soaked throat pack on POTCs following oral and maxillofacial surgery.
Materials And Methods: This was a randomized, triple-blinded, controlled clinical study design on all consecutive patients who had endotracheal intubation and pharyngeal throat packs following major oral and maxillofacial surgery.
Differential effects of chronic unpredictable stress on behavioral and molecular (cortisol and microglia-related neurotranscriptomic) responses in adult leopard (leo) zebrafish.
Fish Physiol Biochem
January 2025
Neurobiology Program, Sirius University of Science and Technology, Sochi, Russia.
Stress plays a key role in mental, neurological, endocrine, and immune disorders. The zebrafish (Danio rerio) is rapidly gaining popularity as s model organism in stress physiology and neuroscience research. Although the leopard (leo) fish are a common outbred zebrafish strain, their behavioral phenotypes and stress responses remain poorly characterized.
View Article and Find Full Text PDFPhysiological responses of pacu (Piaractus mesopotamicus) to intermittent cold exposure: A comprehensive analysis of stress, immunity, antioxidant, and metabolic adaptations.
Fish Physiol Biochem
January 2025
São Paulo State University (UNESP), Aquaculture Center of UNESP, Jaboticabal, Sao Paulo, Brazil.
This study examined the energy-dependent physiological responses, including stress, innate immune, and antioxidant systems, as well as indicators of energy mobilization, in pacu (Piaractus mesopotamicus) exposed to intermittent cold, aiming to assess the correlations between these responses. The fish were acclimated to 28 °C, divided into two groups, a control group maintained at 28 °C, and another exposed to 16 °C for two 24 h periods with a 5-day interval between them. The fish were sampled at six time points: baseline (after acclimatization to 28 °C), 24 h after the 1st exposure to 16 °C, after 5 days of recovery at 28 °C, 24 h after the 2nd exposure to 16 °C, and after 24 and 48 h of recovery at 28 °C.
View Article and Find Full Text PDFAssessment of a new protocol strategy to control the ectoparasitic infestation in Nile tilapia (Oreochromis niloticus) using efficient natural products.
BMC Vet Res
January 2025
Department of Parasitology, Faculty of Veterinary Medicine, Cairo University, Giza, 12211, Egypt.
This study aimed to evaluate alternative in vivo treatment trials using natural products for ectoparasitic infestation on Nile tilapia; these two products were not previously used in the treatment of parasitic fish diseases. So, a total of 400 Oreochromis niloticus (O. niloticus) fish measured 10-15 cm in length; 350 from a fish farm in (Kafr Elsheikh and 50 from Nile River (Al Bahr Al Aazam), Egypt.
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