The effects of retinol and alpha-tocopherol-deficient and supplemented diets on the cytosolic concentration of thiobarbituric acid reactive substances (TBARS) in rat liver have been studied. Physiological lipoperoxidation (LPO) was observed in liver cytosol of control rats (TBARS = 0.315 +/- 0.034 nmol of MDA equivalents/mg of liver cytosolic proteins). In retinol-deficient diets there was a decrease in retinolaemia and the absence of retinol in liver cytosol while cytosolic TBARS increased significantly (P less than 0.001). Vitamin E was not found in cytosolic fractions, except in alpha-tocopherol-supplemented diet rats. alpha-Tocopherol-deficient diets induced an absence of vitamin E in the serum and cytosolic TBARS were increased compared to controls (P less than 0.001). Supplementation of the diet with retinol and alpha-tocopherol or both in combination induced a significant decrease in liver cytosolic TBARS (P less than 0.001). Finally the combination of low dietary supplementation with retinol and alpha-tocopherol (ten times the normal diet each) induced the maximum anti-LPO effect.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1080/02652039209374042 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Absorption study of fat-soluble vitamins into dipalmitoylphosphatidylcholine (DPPC) bilayer by MD simulations.
J Mol Graph Model
March 2025
Department of Chemistry, Faculty of Science and Technology, Muban ChomBueng Rajabhat University, Chom Bueng, Ratchaburi, 70150, Thailand. Electronic address:
Retinol, α-tocopherol and phylloquinone (vitamins A, E, and K) are presented in high concentrations within the chloroplast and leaves of most plants. They are fat-soluble vitamins and absorb similarly to other dietary lipids. Because the molecular mechanism of retinol, α-tocopherol, and phylloquinone absorption is still unknown, this work aims to investigate the distribution of these vitamins at the water/membrane interface using molecular dynamics (MD) simulations.
View Article and Find Full Text PDFEdible caterpillars ( and ) as emerging source of nutrients and bioactive compounds.
Future Foods
December 2024
International Centre of Insect Physiology and Ecology, P.O. Box 30772 - 00100, Nairobi, Kenya.
Globally, despite the commercial and cultural importance of edible caterpillars ( and ), comprehensive information on their dietary and therapeutic benefits has not been fully explored. The study was aimed at evaluating the nutritional composition and bioactive compounds profile of two important edible caterpillars ( and ) in Africa. Our results demonstrated that and are capable of amplifying host plant protein (17 %) by 4.
View Article and Find Full Text PDFAntioxidants and the risk of metabolic dysfunction-associated steatotic liver disease: results of National Health and Nutrition Examination Survey and two-sample Mendelian randomization analyses.
Eur J Gastroenterol Hepatol
February 2025
Department of Endocrinology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
Background: The link between antioxidants and metabolic dysfunction-associated steatotic liver disease (MASLD) is a topic of considerable discussion in the field of observational studies, with the exact causal connections still being unclear.
Methods: In this investigation, a cohort consisting of 17 061 participants from the National Health and Nutrition Examination Surveys was studied. Initially, a cross-sectional analysis was carried out to examine the relationship between the CDAI and MASLD.
Enrichment of Vitamin A and Vitamin E in Sweet Corn Kernels Through Genomics-Assisted Introgression of Mutant Version of crtRB1 and vte4 Genes.
Appl Biochem Biotechnol
December 2024
ICAR-Indian Agricultural Research Institute, New Delhi, 110012, India.
Recessive shrunken2 (sh2)-based sweet corn is preferred worldwide as it possesses higher sugar and extended shelf life. However, traditional sh2-based sweet corn is poor in vitamin A and vitamin E. Here, parental lines of two sh2-based sweet corn hybrids, viz.
View Article and Find Full Text PDFEffect of Different Dietary Doses of Black Soldier Fly Meal on Performance and Egg Quality in Free-Range Reared Laying Hens.
Animals (Basel)
November 2024
Granja Monte Encinar, El Barraco, 05110 Ávila, Spain.
(1) Background: Given the problems currently posed by the use of soybean meal in poultry feeding, its replacement with black soldier fly (BSF) meal may be a suitable strategy. Therefore, this study evaluated the effect of this dietary replacement on laying performance, egg quality, and yolk nutritional composition in free-range reared hens. (2) Methods: Three diets were formulated: a control diet with 210 g/kg of soybean meal, a diet with 105 g/kg of soybean meal and 80 g/kg of BSF meal, and a diet with 160 g/kg of BSF meal.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!