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Deletion of pagL and arnT genes involved in LPS structure and charge modulation in the Salmonella genome confer reduced endotoxicity and retained efficient protection against wild-type Salmonella Gallinarum challenge in chicken.
Vet Res
January 2025
College of Veterinary Medicine, Jeonbuk National University, Iksan Campus, Iksan, 54596, Republic of Korea.
Fowl typhoid (FT) poses a significant threat to the poultry industry and can cause substantial economic losses, especially in developing regions. Caused by Salmonella Gallinarum (SG), vaccination can prevent FT. However, existing vaccines, like the SG9R strain, have limitations, including residual virulence and potential reversion of pathogenicity.
View Article and Find Full Text PDFMogroside V protects Lipopolysaccharides-induced lung inflammation chicken via suppressing inflammation mediated by the Th17 through the gut-lung axis.
J Anim Sci
December 2024
Research Centre for Livestock Environmental Control and Smart Production, College of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.
Lipopolysaccharide (LPS) exposure triggers pulmonary inflammation, leading to compromised lung function in broiler. As amplified by policy restrictions on antibiotic usage, seeking antibiotic alternatives has become imperative. Mogroside V (MGV) has been reported to have a beneficial role in livestock and poultry production due to its remarkable anti-inflammatory effects.
View Article and Find Full Text PDFKnowledge and perceptions of blood donors of the Western Cape Blood Services, South Africa, toward vaginal sample donation for biobanking.
Front Reprod Health
November 2024
Division of Medical Microbiology, Department of Pathology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
Article Synopsis
- Depletion of species in the vaginal tract leads to bacterial vaginosis (BV), which is linked to poor reproductive health and higher risk of STIs; current antibiotic treatments have low success rates.
- A study conducted in Cape Town explored blood donors' knowledge and attitudes toward vaginal microbiota transplantation (VMT) as a potential alternative treatment for BV through a questionnaire.
- Results showed a significant majority (86%) of women were open to donating vaginal samples, with willingness increased by a belief in helping others and prior knowledge of healthy vaginal microbiomes; concerns about discomfort and embarrassment affected those unwilling to donate.
Transplantation of fecal microbiota from low to high residual feed intake chickens: Impacts on RFI, microbial community and metabolites profiles.
Poult Sci
November 2024
State Key Laboratory of Swine and Poultry Breeding Industry, Guangdong Key Laboratory of Animal Breeding and Nutrition, Institute of Animal Science, Guangdong Academy of Agricultural Sciences, Guangzhou, China.. Electronic address:
Improving feed efficiency is vital to bolster profitability and sustainability in poultry production. Although several studies have established links between gut microbiota and feed efficiency, the direct effects remain unclear. In this study, two distinct lines of Huiyang bearded chickens, exhibiting significant differences in residual feed intake (RFI), were developed after 15 generations of selective breeding.
View Article and Find Full Text PDFAlteration in the Gut Microbiota of Chickens Resistant to Infection.
Microorganisms
October 2024
Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Key Laboratory of Animal Parasitology of Ministry of Agriculture, Minhang, Shanghai 200241, China.
Article Synopsis
- Avian coccidiosis is a major poultry disease causing significant economic losses, highlighting the importance of gut microbiota in managing the illness and developing new treatments.
- The study found that immunizing chickens with a low dose of the coccidia led to complete immunity and changes in gut microbiota composition, contributing to resistance against infection.
- Gene sequencing of intestinal contents revealed specific changes in microbial populations that may play a role in enhancing immunity, paving the way for future vaccine development and microbiome research.
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