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The Diagnostic Utility of Host RNA Biosignatures in Adult Patients With Sepsis: A Systematic Review and Meta-Analysis.
Crit Care Explor
February 2025
Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, United Kingdom.
Objectives: Sepsis is a life-threatening medical emergency, with a profound healthcare burden globally. Its pathophysiology is complex, heterogeneous and temporally dynamic, making diagnosis challenging. Medical management is predicated on early diagnosis and timely intervention.
View Article and Find Full Text PDFCorrection: Fluid accumulation syndrome in sepsis and septic shock: pathophysiology, relevance and treatment-a comprehensive review.
Ann Intensive Care
January 2025
First Department of Anaesthesiology and Intensive Therapy, Medical University of Lublin, Lublin, Poland.
Developmental functional brain network abnormalities in autism spectrum disorder comorbid with attention deficit hyperactivity disorder.
Eur J Pediatr
January 2025
Department of Developmental and Behavioral Pediatrics, Children's Medical Center, The First Hospital of Jilin University, Jilin University, Changchun, China.
Unlabelled: Autism spectrum disorder (ASD) and attention deficit hyperactivity disorder (ADHD) often co-occur. Developmental stages significantly influence the variations in brain alterations. However, whether ASD comorbid with ADHD (ASD + ADHD) represents a unique neural characteristic from ASD without comorbid ADHD (ASD-alone), or instead manifests a shared neural correlate associated with ASD across diverse age cohorts remain unclear.
View Article and Find Full Text PDFInadequate sleep hygiene as a key factor in poor sleep quality in systemic sclerosis: an observational, cross-sectional study.
Rheumatol Int
January 2025
Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology, Kocaeli University, Kocaeli, Turkey.
This study aims to investigate the relationship between sleep hygiene and sleep quality in patients with systemic sclerosis (SSc) and to compare the sleep hygiene and sleep quality outcomes across three distinct groups: SSc patients, rheumatoid arthritis (RA) patients, and healthy controls (HC). This study employed an observational, cross-sectional, and parallel group design. SSc-related and RA-related variables, depression and anxiety were assessed.
View Article and Find Full Text PDFSerotonin Receptors Polymorphisms Are Associated With Cyclic Vomiting Syndrome.
Neurogastroenterol Motil
January 2025
Division of Gastroenterology, Hepatology and Nutrition, The Ohio State University, Columbus, Ohio, USA.
Background: Cyclic vomiting syndrome (CVS) is a disorder characterized by sudden, recurrent episodes of severe nausea and vomiting. The pathophysiology of CVS is not known but genetic factors that regulate emetic neurocircuitry have been proposed. The aim of this study was to investigate whether different variations in genes encoding serotonin receptors (HTRs) are associated with susceptibility to CVS and/or CVS symptoms.
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