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Comparing approaches for predicting behavioural speech-in-noise performance using cortical responses to unattended stimuli.
Hear Res
January 2025
Institute of Sound and Vibration Research, University of Southampton, Southampton, United Kingdom.
The cortical tracking of the acoustic envelope is a phenomenon where the brain's electrical activity, as recorded by electroencephalography (EEG) signals, fluctuates in accordance with changes in stimulus intensity (the acoustic envelope of the stimulus). Understanding speech in a noisy background is a key challenge for people with hearing impairments. Speech stimuli are therefore more ecologically valid than clicks, tone pips, or speech tokens (e.
View Article and Find Full Text PDFDevelopment and Evaluation of a Mindfulness-Based Mobile Intervention for Perinatal Mental Health: Randomized Controlled Trial.
J Med Internet Res
January 2025
Department of Psychiatry, Catholic Kwandong University International St. Mary's Hospital, Catholic Kwandong University College of Medicine, Incheon, Republic of Korea.
Background: Perinatal mental health problems, such as anxiety, stress, and depression, warrant particularly close monitoring and intervention, but they are often unaddressed in both obstetric and psychiatric clinics, with limited accessibility and treatment resources. Mobile health interventions may provide an effective and more accessible solution for addressing perinatal mental health. Development and evaluation of a mobile mental health intervention specifically for pregnant women are warranted.
View Article and Find Full Text PDFConformational Antibodies to Proteolipid Protein-1 and Its Peripheral Isoform DM20 in Patients With CNS Autoimmune Demyelinating Disorders.
Neurol Neuroimmunol Neuroinflamm
March 2025
Neuroimmunology Laboratory and Neuroimmunology Research Section, IRCCS Mondino Foundation, Pavia, Italy.
Background And Objectives: Antibodies to proteolipid protein-1 (PLP1-IgG), a major central myelin protein also expressed in the peripheral nervous system (PNS) as the isoform DM20, have been previously identified mostly in patients with multiple sclerosis (MS), with unclear clinical implications. However, most studies relied on nonconformational immunoassays and included few patients with non-MS CNS autoimmune demyelinating disorders (ADDs). We aimed to investigate conformational PLP1-IgG in the whole ADD spectrum.
View Article and Find Full Text PDFImproved Items for Estimating SF-36 Profile and Summary Component Scores: Construction and Validation of an 8-item QOL General (QGEN) Survey.
Med Care
January 2025
John Ware Research Group (JWRG), Watertown, MA.
Background: Comprehensive health-related quality of life (QOL) assessment under severe respondent burden constraints requires improved single-item scales for frequently surveyed domains. This article documents how new single-item-per-domain (SIPD) QOL General (QGEN-8) measures were constructed for domains common to SF-36 and results from the first psychometric tests comparing scores for the new measure in relation to those for the SF-36 profile and summary components.
Research Design: Online NORC surveys of adults, ages 19-93 (mean=52 y) representing the US population in 2020 (N=1648) included QGEN-8 and SF-36 items measuring physical (PF), social (SF), role physical (RP) and role emotional (RE) functioning and feelings of bodily pain (BP), vitality (VT), and mental health (MH).
Left Insula and Right Middle Temporal Gyrus Dominate Cortical Network Discriminating Arousal-dependent Emotions.
Adv Sci (Weinh)
January 2025
Department of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, 100053, China.
Emotion processing is an integral part of everyone's life. The basic neural circuits involved in emotion perception are becoming clear, though the emotion's cognitive processing remains under investigation. Utilizing the stereo-electroencephalograph with high temporal-spatial resolution, this study aims to decipher the neural pathway responsible for discriminating low-arousal and high-arousal emotions.
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