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Individual FiO guided by SO prevents hyperoxia and reduces postoperative atelectasis in colorectal surgery: A randomized controlled trial.

J Clin Anesth

December 2024

Department of Anesthesiology, Second Affiliated Hospital of Harbin Medical University, China; The Key Laboratory of Anesthesiology and Intensive Care Research of Heilongjiang Province, China. Electronic address:

Study Objective: To determine whether individualized fraction of inspired oxygen (iFiO) improves pulmonary atelectasis after elective laparoscopic colorectal surgery relative to 60 % FiO.

Design: This was a single-center, prospective, randomized study.

Setting: This study was conducted in a single tertiary care hospital in China.

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Introduction: Pericardial effusion (PE) is an abnormal accumulation of fluid in the pericardial space, which, if severe, is associated with high mortality. The causes are diverse, including infective and non-infective. Few studies have looked at the spectrum of severity and causes in Northern Nigeria.

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Background: In December 2019, COVID-19 emerged in China and spread rapidly throughout the world, including India. So far, India has witnessed three spells of the disease, termed the first, second, and third waves; although the first two waves were significant in terms of severity, mortality, and need for respiratory support, the third wave had no significant impact and most people recovered without being admitted to the hospital. The present study aimed to discuss the clinical demographic characteristics and in-hospital outcomes of COVID-19 patients and their comparisons between the first and second waves.

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Rituximab Safety Profile: A Seven-Year Retrospective Analysis From Southern India.

Cureus

November 2024

Pharmacovigilance, Regional Training Center and ADR (Adverse Drug Reaction) Monitoring Center, Amrita Institute of Medical Science, Amrita Vishwa Vidyapeetham, Ernakulam, IND.

Objective: This study aimed to analyze the pattern, severity, and outcomes of adverse drug reactions (ADRs) associated with rituximab use reported to a regional pharmacovigilance center in Kerala, India.

Methods: This retrospective study analyzed rituximab-associated ADRs reported from 2017 to 2023. ADRs were assessed using the WHO-UMC criteria for causality and the Modified Hartwig Siegel Scale for severity.

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Introduction Despite efforts, tuberculosis (TB) remains a major public health problem in developing countries, and India alone accounts for most of the global TB cases. Although the treatment for TB is highly successful, a significant number of TB patients in India do not complete their assigned treatment. Social support has a key influence on medication adherence for chronic illnesses like diabetes, asthma, HIV, hypertension, cardiovascular diseases, and TB.

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