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Chapter 4: DIFFERENTIAL DIAGNOSIS of PRIMARY HYPERPARATHYROIDISM.
Ann Endocrinol (Paris)
January 2025
Service d'Endocrinologie, Diabétologie, Métabolisme, Nutrition; Hôpital Huriez, CHU Lille; Inserm U1190, Institut Génomique Européen pour le Diabète, Université de Lille, F-59000 Lille, France. Electronic address:
The differential diagnosis of primary hyperparathyroidism can be considered clinically, biologically and radiologically. Clinically, primary hyperparathyroidism should be suspected in case of diffuse pain, renal lithiasis, osteoporosis, repeated fracture, cognitive or psychiatric disorder, or disturbance of consciousness. Nevertheless, the differential diagnosis of primary hyperparathyroidism is mainly biological, particularly in atypical forms, which must be differentiated from hypercalcemia with hypocalciuria or non- elevated PTH on the one hand, and from normo-calcemia with elevated PTH, hypophosphatemia or hypercalciuria on the other.
View Article and Find Full Text PDFInfluence of androgen receptor on bone health in transgender adults: insights from the COMET study.
J Endocrinol Invest
January 2025
Regional Reference Center for Gender Incongruence (CRRIG) of the Veneto Region, University Hospital of Padova, Padua, Italy.
Purpose: Previous studies show that transgender and gender-diverse (TGD) individuals, especially those assigned male at birth (AMAB), often have low bone mineral density (BMD) before beginning gender-affirming hormone therapy (GAHT). The reasons for this are not fully understood, and the potential role of androgen receptor (AR) polymorphisms - known to affect bone density in the general population - has not been explored. This study aims to assess the impact of AR polymorphisms on bone health in the TGD population.
View Article and Find Full Text PDF[Vitamin D Deficiency In Advanced Breast Cancer Risk In Mali].
Mali Med
November 2024
Université Mohammed V de Rabat, Faculté de médecine et de pharmacie, Rabat-Maroc.
Aims: The aim of this study was to determine the association between vitamin D deficiency and advanced BC in a Malian women population.
Methods: This is a prospective cross-sectional study, conducted during 4 months, from August 2021 to November 2021. The assays were performed on immunodiagnostic and biochemistry devices in Rodolphe Merieux Laboratory.
Hypovitaminosis D in university workers in Southern Ecuador: interactions between gender and lifestyle.
Front Nutr
September 2024
Clinical Laboratory Service, Juan Manuel Márquez Pediatric Teaching Hospital, Havana, Cuba.
Background: Hypovitaminosis D may be common in tropical countries and is linked to disorders of phospho-calcium metabolism, rickets, muscle pain, immune system deficiencies, and increased susceptibility to microbial infections.
Objective: To assess the prevalence of hypovitaminosis D in apparently healthy university workers in Loja, Ecuador.
Methods: A cross-sectional study was completed in a private Ecuadorian university from May 2023 to September 2023, involving 440 participants.
Effect of long-term proton pump inhibitors on phosphocalcium metabolism and bone mineral density.
Future Sci OA
May 2024
Department of Gastroenterology & Hepatology, Hedi Chaker University Hospital, Sfax, Tunisia.
Although Proton pump inhibitors (PPIs) are well-tolerated, their long-term use may be associated with decreased bone mass. This is a case-control study including patients treated with PPIs (>1 year) and control subjects who have not received PPIs treatment. A total of 90 patients and 90 matched controls were included.
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