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Proinflammatory synergy between protease and superantigen streptococcal pyogenic exotoxins.
Infect Immun
January 2025
Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, Georgia, USA.
Streptococcal pyogenic exotoxins (Spe proteins) secreted by (group A , GAS) are responsible for scarlet fever and streptococcal toxic shock syndrome. Most Spes are superantigens that cause excessive inflammation by activating large numbers of T cells. However, Streptococcal pyogenic exotoxin B (SpeB) is an exception, which is pro-inflammatory through its protease activity.
View Article and Find Full Text PDFAortic valve infective endocarditis due to : A case report.
IDCases
January 2023
Department of Infectious Disease, Baystate Medical Center, Springfield, MA, USA.
Group A is a common cause of pharyngitis, scarlet fever, glomerulonephritis, and various skin infections. However, there have only been a few reports of Group A (GAS) associated with infective endocarditis. We present a case of a 31-year-old male who presented to the hospital with a few days of weakness and myalgias after recently receiving treatment with azithromycin for GAS pharyngitis as an outpatient.
View Article and Find Full Text PDFDecreased Antibiotic Consumption Coincided with Reduction in Bacteremia Caused by Bacterial Species with Respiratory Transmission Potential during the COVID-19 Pandemic.
Antibiotics (Basel)
May 2022
Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.
Nonpharmaceutical interventions implemented during the COVID-19 pandemic (2020−2021) have provided a unique opportunity to understand their impact on the wholesale supply of antibiotics and incidences of infections represented by bacteremia due to common bacterial species in Hong Kong. The wholesale antibiotic supply data (surrogate indicator of antibiotic consumption) and notifications of scarlet fever, chickenpox, and tuberculosis collected by the Centre for Health Protection, and the data of blood cultures of patients admitted to public hospitals in Hong Kong collected by the Hospital Authority for the last 10 years, were tabulated and analyzed. A reduction in the wholesale supply of antibiotics was observed.
View Article and Find Full Text PDFChromatographic profiles and antimicrobial activity of the essential oils obtained from some species and cultivars of the tribe (.
Saudi J Biol Sci
November 2021
Department of Analytical Chemistry, University of Opole, Opole 45-052, Poland.
The present study was focused on the chemical composition and antimicrobial activity of the essential oils (EsO) obtained from five representatives grown in the south of Ukraine. Among them are L. (cultivar 'Cambridge Scarlet'), (cultivar '2/6-07') (cultivar 'Jalos') and L.
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