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Article Synopsis
  • The study focused on evaluating the effectiveness of CaneCPI-5, a sugarcane cystatin, in preventing erosion and tooth wear compared to other rinses like deionized water and Elmex®.
  • Nine volunteers participated in a controlled trial using a Reflectometer Optipen to measure the surface reflection intensity of their teeth after rinsing with different solutions and experiencing erosive challenges with citric acid.
  • Results indicated that CaneCPI-5 provided protection against tooth erosion similar to Elmex®, and both showed significantly better results than the negative control, making the Reflectometer Optipen a reliable clinical assessment tool.
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Guttate psoriasis triggered by perianal streptococcal infection.

Clin Exp Dermatol

July 2017

Department of Dermatology, University Medical Center Utrecht, Wilhelmina Children's Hospital, the Netherlands.

The association of guttate psoriasis (GP) with streptococcal pharyngitis is well accepted. However, less is known about the association with perianal streptococcal infection. We report a case of a 19-month-old boy with GP after a preceding perianal streptococcal dermatitis, with no clinical signs of a streptococcal pharyngitis.

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Actinomycosis of the abdominal wall after cholecystectomy: transferral theory.

Neth J Med

December 2016

Departments of Internal Medicine and Department of Pathology, VU University Medical Center, Amsterdam, the Netherlands.

Abdominal actinomycosis is a rare disease caused by Gram-positive anaerobic Actinomyces bacteria. Here, we present a patient with an intrauterine contraceptive device who developed a long lasting and unexplained recurrent, painful abdominal swelling a few months after a laparoscopic cholecystectomy.

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Antibiotic drug use of children in the Netherlands from 1999 till 2005.

Eur J Clin Pharmacol

September 2008

Department of Social Pharmacy, Pharmacoepidemology and Pharmacotherapy, University of Groningen, Groningen, the Netherlands.

Objective: Antibiotics are the most commonly prescribed drugs used by children. Excessive and irrational use of antibiotic drugs is a world-wide concern. We performed a drug utilization study describing the patterns of antibiotic use in children aged 0-19 years between 1999 and 2005 in the Netherlands.

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An open-label randomised clinical trial was designed to compare the efficacy and tolerance of levofloxacin and ciprofloxacin plus phenethicillin for the prevention of bacterial infections in patients with high-risk neutropenia, and to monitor the emergence of antimicrobial resistance. Adult patients (n = 242) scheduled to receive intensive treatment for haematological malignancies were assigned randomly to receive oral prophylaxis with either levofloxacin 500 mg once-daily (n = 122), or ciprofloxacin 500 mg twice-daily plus phenethicillin 250 mg four-times-daily (n = 120). The primary endpoint was failure of prophylaxis, defined as the first occurrence of either the need to change the prophylactic regimen or the initiation of intravenous broad-spectrum antibiotics.

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