Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/0006-291x(63)90092-5 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Integrated physiological, transcriptomic and metabolomic analyses reveal potential mechanisms of potato tuber dormancy release.
Physiol Plant
January 2025
School of Agriculture, Yunnan University, Kunming, Yunnan, China.
Regulating potato tuber dormancy is crucial for crop productivity and food security. We conducted the first comprehensive physiological, transcriptomic, and metabolomic investigations of two varieties of long and short dormant potato tubers in order to clarify the mechanisms of dormancy release. In the current study, three different dormant stages of UGT (ungerminated tubers), MGT (minimally germinated tubers), and GT (germinated tubers) were obtained by treatment with the germination promoter gibberellin A and the germination inhibitor chlorpropham.
View Article and Find Full Text PDFMyc hyperactivation coordinately regulates numerous metabolic processes to drive lymphomagenesis. Here, we elucidate the temporal and functional relationships between the medley of pathways, factors, and mechanisms that cooperate to control redox homeostasis in Myc-overexpressing B cell lymphomas. We find that Myc overexpression rapidly stimulates the oxidative pentose phosphate pathway (oxPPP), nucleotide synthesis, and mitochondrial respiration, which collectively steers cellular equilibrium to a more oxidative state.
View Article and Find Full Text PDFInvestigation of the Molecular Mechanism of Asthma in Meishan Pigs Using Multi-Omics Analysis.
Animals (Basel)
January 2025
Institute of Animal Husbandry and Veterinary Science, Shanghai Academy of Agricultural Sciences, Shanghai 201106, China.
Asthma has been extensively studied in humans and animals, but the molecular mechanisms underlying asthma in Meishan pigs, a breed with distinct genetic and physiological characteristics, remain elusive. Understanding these mechanisms could provide insights into veterinary medicine and human asthma research. We investigated asthma pathogenesis in Meishan pigs through transcriptomic and metabolomic analyses of blood samples taken during autumn and winter.
View Article and Find Full Text PDFIntegrated omics analyses elucidate acetaminophen biodegradation by Enterobacter sp. APAP_BS8.
J Environ Manage
January 2025
Department of Botany, Institute of Science, Banaras Hindu University, Varanasi, 221005, India. Electronic address:
Acetaminophen (APAP) is an extensively consumed over-the-counter and prescribed medication and a constituent of many active pharmaceutical compounds as well as personal care products. Its wide-scale prevalence in the environment due to inefficient treatment technologies has classified APAP as a contaminant of emerging concern. Thus, it is imperative to explore efficient and sustainable methods for remediation of contaminated environments.
View Article and Find Full Text PDFExploring the causal role of plasma metabolites and metabolite ratios in prostate cancer: a two-sample Mendelian randomization study.
Front Mol Biosci
January 2025
Department of Clinical Laboratory, The First People's Hospital of Lianyungang, The Affiliated Lianyungang Hospital of Xuzhou Medical University, The First Affiliated Hospital of Kangda College of Nanjing Medical University, Lianyungang, Jiangsu, China.
Background: Prostate cancer (PCa), the most prevalent malignant neoplasm in males, involves complex biological mechanisms and risk factors, many of which remain unidentified. By employing a novel two-sample Mendelian randomization (MR) approach, this study aims to elucidate the causal relationships between the circulating metabolome and PCa risk, utilizing comprehensive data on genetically determined plasma metabolites and metabolite ratios.
Methods: For the MR analysis, we utilized data from the GWAS Catalog database to analyze 1,091 plasma metabolites and 309 ratios in relation to PCa outcomes within two independent GWAS datasets.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!