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Reactive Arthritis: Update.
Curr Clin Microbiol Rep
September 2020
Service of Rheumatology A, El Ayachi Hospital, University Mohamed V Rabat, 11150 Salé, Morocco.
Purpose Of Review: The aim of this paper is to provide an overview about reactive arthritis, with an update regarding pathophysiology and therapeutic approach of the disease, outlining the clinical features and diagnostic approach, based on recent literature review.
Recent Findings: Reactive arthritis is considered to be part of the spectrum of the spondyloarthritis. Its epidemiology is changing worldwide due to several reasons, among them are as follows: different diagnosis approach and clinical presentations, different grades of infection, microbiome changes, etc.
Chlamydia-Induced Reactive Arthritis: Disappearing Entity or Lack of Research?
Curr Rheumatol Rep
November 2019
School of Medicine, Wayne State University, Detroit, MI, USA.
Purpose Of Review: Recent studies regarding the frequency of Chlamydia-induced reactive arthritis (ReA) are reviewed, with a focus on the question of whether the entity is in fact disappearing or whether it is simply being underdiagnosed/underreported. Epidemiological reports indicate diversity in the frequency of Chlamydia-associated ReA in various parts of the world, with evidence of declining incidence in some regions.
Recent Findings: The hypothesis that early effective treatment with antibiotics prevents the manifestation of Chlamydia-associated ReA requires further investigation.
Chlamydia-induced reactive arthritis diagnosed during gout flares: A case report and cumulative effect of inflammatory cytokines on chronic arthritis.
Medicine (Baltimore)
October 2019
Division of Advanced Preventive Medical Sciences, Department of Immunology and Rheumatology.
Rationale: The pathology of gouty arthritis and reactive arthritis (ReA) partially overlaps, and both diseases are characterized by the production of inflammatory cytokines associated with the activation of monocytes and macrophages. However, the precise cytokine profile of cases with a coexistence of both diseases is unknown, and there are few reports on the course of treatment in patients with both gouty arthritis and ReA.
Patient Concerns: A 39-year-old man with a recurrent episode of gouty arthritis presented prednisolone-resistant polyarthritis with high level of C-reactive protein (CRP).
[Reactive arthritis].
Rev Med Suisse
March 2018
Service de rhumatologie, Département de l'appareil locomoteur, CHUV, 1011 Lausanne.
Reactive arthritis is usually regarded as a form of spondylarthritis. Patients generally present with an acute asymmetrical oligoarthritis following an episode of diarrhea or urethritis. The most frequent involved pathogens are Salmonella, Shigella, Campylobacter and Chlamydia trachomatis.
View Article and Find Full Text PDFRecent advances and future directions in understanding and treating Chlamydia-induced reactive arthritis.
Expert Rev Clin Immunol
March 2017
b Department of Immunology and Microbiology , Wayne State University School of Medicine, Detroit , MI , USA.
Reactive arthritis (ReA) is an inflammatory disease that can follow gastrointestinal or genitourinary infections. The primary etiologic agent for post-venereal ReA is the bacterium Chlamydia trachomatis; its relative, C pneumoniae, has also been implicated in disease induction although to a lesser degree. Studies have indicated that the arthritis is elicited by chlamydiae infecting synovial tissue in an unusual biologic state designated persistence.
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