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Disease burden of tuberculosis in China from 1990 to 2021 and its prediction to 2036.
Front Public Health
January 2025
Department of Public Health, China University of Geosciences Wuhan Hospital, Wuhan, China.
Background: Tuberculosis (TB) is one of the oldest infectious diseases and continues to be a major killer of human beings. This paper was designed to provide insights into the disease burden of TB.
Methods: The data was retrieved and downloaded from the latest GBD database.
Tuberculosis disease burden in China: a spatio-temporal clustering and prediction study.
Front Public Health
January 2025
Institute of Occupational Health and Environmental Health, School of Public Health, Lanzhou University, Lanzhou, China.
Introduction: The primary aim of this study is to investigate and predict the prevalence and determinants of tuberculosis disease burden in China. Leveraging high-quality data sources and employing a methodologically rigorous approach, the study endeavors to enhance our understanding of tuberculosis control efforts across different regions of China. First, through nationwide spatio-temporal cluster analysis, we summarized the status of tuberculosis burden in various regions of China and explore the differences, thereby providing a basis for formulating more targeted tuberculosis prevention and control policies in different regions; Subsequently, using a time series-based forecasting model, we conducted the first-ever national tuberculosis burden trend forecast to offer scientific guidance for timely adjustments in planning and resource allocation.
View Article and Find Full Text PDFHigh risk of drug-resistant tuberculosis in IGRA-negative contacts: should preventive treatment be considered?
Infection
January 2025
Department of Clinical Infectious Diseases, Research Center Borstel, Leibniz Lung Center, Parkallee 35, Borstel, Germany.
Purpose: Deciding whether to provide preventive treatment to contacts of individuals with multidrug-resistant (MDR) tuberculosis is complex.
Methods: We present the diagnostic pathways, clinical course and outcome of tuberculosis treatment in eight siblings from a single family. Tuberculosis disease was diagnosed by Mycobacterium tuberculosis culture and molecular detection of M.
Trends in tuberculosis mortality among older adults in China, 2004-2021: a Joinpoint regression and age-period-cohort analysis.
Front Public Health
January 2025
Office of Education and Training (Graduate School), Chinese Center for Disease Control and Prevention, Beijing, China.
Background: Tuberculosis (TB) remains a major public health problem in China and globally, particularly among older adults. This study aimed to examine secular trends in TB mortality among older adults in China and the net effects of age, period, and cohort.
Methods: Data from the National Disease Surveillance Points (DSPs) system were analyzed using Joinpoint regression to determine annual changes in TB mortality among individuals aged 60 years and older from 2004 to 2021.
Magnitude of opportunistic infections and associated factors among HIV-infected individuals attending care and treatment clinics in Dar es Salaam, Tanzania: a hospital-based cross-sectional study.
BMJ Open
January 2025
Department of Microbiology and Immunology, Muhimbili University of Health and Allied Sciences, Dar es Salaam, United Republic of Tanzania.
Objectives: This study aims to assess the magnitude of opportunistic infection (OI) and to identify factors associated with OIs among people living with HIV (PLHIV) on antiretroviral treatment (ART), attending HIV care and treatment clinics.
Design: A hospital-based cross-sectional study.
Setting: The study was conducted at Muhimbili National Hospital, Mwananyamala and Temeke Regional Referral Hospitals, in Dar es Salaam, Tanzania.
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