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Recurrence of a primary xanthoma of the humerus in a 9-year-old normolipidemic child.
Arch Pediatr
October 2019
UNICAEN, department of pediatric orthopedic surgery, Normandie université, CHU de Caen Normandie, 14000 Caen France.
Xanthomas are rare bone tumors that occur more often in patients with hyperlipidemia or metabolic disorders. We report the case of a 9-year-old child presenting with right shoulder pain after a trauma. A benign osteolytic lesion was found in the proximal humeral metaphysis.
View Article and Find Full Text PDFXanthogranulomatous osteomyelitis of the humerus in a pediatric patient with Alagille syndrome: a case report and literature review.
Skeletal Radiol
October 2017
Department of Pathology, Children's Hospital of Philadelphia, 5NW11, 3401 Civic Center Blvd, Philadelphia, PA, 19104, USA.
Xanthogranulomatous osteomyelitis (XO) is an exceedingly rare disease characterized by infiltration of histiocytes and foamy macrophages. Both on gross examination and on radiographs, XO can mimic malignancy. We describe the case of a 5-year-old female with Alagille syndrome who presented with a pathologic fracture of the right humerus.
View Article and Find Full Text PDFXanthoma of bone: a case report.
Case Rep Endocrinol
September 2012
Nuclear Medicine Department, University of Mohammed V-Souissi, Rabat, Morocco.
Bone xanthoma is a rare disease due to the presence of cholesterol deposits in the bone. We report a case of a 56-year-old patient who was hospitalized in orthopedic department for fracture on the left humerus. Histological examination of bone biopsy performed at this site has objectified cholesterol deposits.
View Article and Find Full Text PDFXanthogranulomatous osteomyelitis.
J Orthop Traumatol
December 2012
Department of Orthopedic Surgery, Isfahan University of Medical Sciences, Isfahan, Iran.
Xanthogranulomatous osteomyelitis is a rare type of inflammatory process which is characterized by composition of immune cell aggregation on histological studies. Delayed-type hypersensitivity reaction of cell-mediated immunity may be implicated in its pathogenesis. Gross and radiological examination can mimic malignancy, and differentiation should be confirmed by histopathological evaluation.
View Article and Find Full Text PDFXanthoma of bone associated with lipoprotein lipase deficiency.
Skeletal Radiol
December 2008
Department of Orthopaedic Surgery, Juntendo University School of Medicine, Hongo 2-1-1, Bunkyo-ku, Tokyo, 113-8421, Japan.
Lipoprotein lipase (LPL) deficiency is an extremely rare congenital metabolic disorder with an accumulation of chylomicrons in the blood. We encountered a patient with an LPL deficiency leading to multiple bone xanthomas associated with hyperlipidemia. Radiographs and MRI of the humerus and femur revealed symmetrical bone lesions, and there is a possibility that these symmetrical lesions may therefore be a characteristic feature for this disorder.
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