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Stimulant-involved overdose deaths: Constructing dynamic hypotheses.
Int J Drug Policy
January 2025
MGH Institute for Technology Assessment, Harvard Medical School, Boston, MA, 02144, USA. Electronic address:
The overdose epidemic in the United States is evolving, with a rise in stimulant (cocaine and/or methamphetamine)-only and opioid and stimulant-involved overdose deaths for reasons that remain unclear. We conducted interviews and group model building workshops in Massachusetts and South Dakota. Building on these data and extant research, we identified six dynamic hypotheses, explaining changes in stimulant-involved overdose trends, visualized using causal loop diagrams.
View Article and Find Full Text PDFRelationship between structural properties and biological activity of (-)-menthol and some menthyl esters.
Comput Biol Chem
January 2025
Department of Natural Sciences, Novosibirsk State University, Novosibirsk 630090, Russia. Electronic address:
Menthol is a naturally occurring cyclic terpene alcohol and is the major component of peppermint and corn mint essential oils extracted from Mentha piperita L. and Mentha arvensis L..
View Article and Find Full Text PDFInvestigating the LiO-AlO-BO matrix: A promising approach for immobilizing radioactive waste.
Appl Radiat Isot
January 2025
Department of Physics, Faculty of Science, Universiti Teknologi Malaysia, 81300, Skudai, Johor, Malaysia.
Dealing with radioactive waste, particularly from various industrial processes, poses significant challenges. This paper explores the use of lithium aluminate borate (Li-Al-B) glass matrix as an alternative method for immobilizing radioactive waste, focusing specifically on waste generated in tin smelting industries, known as tin slag. The study primarily concentrates on transforming tin slag, a byproduct abundant in Natural Occurring Radioactive Material (NORM), into a stable and safe form for disposal.
View Article and Find Full Text PDFNew cinnamic acid sugar esters as potential UVB filters: Synthesis, cytotoxicity, and physicochemical properties.
Carbohydr Res
January 2025
Department of Biomolecular Sciences, University of Urbino "Carlo Bo", Campus Scientifico E. Mattei, via Ca' Le Suore 2, 61029, Urbino, PU, Italy. Electronic address:
Cinnamic Acid Sugar Ester Derivatives (CASEDs) are a class of natural compounds that exhibit several interesting biological activities. However, to date, no examples of their use in sunscreen formulations have been reported. Here, we describe the synthesis of a series of novel cinnamic acid esters of glucose (4a-g), ribose (4h) and lactose (4i) starting from the respective acetals 3.
View Article and Find Full Text PDFAggressiveness and phylogenetic relationship of associated with crown and root rot in pyrethrum plants.
Plant Dis
January 2025
The University of Melbourne, Faculty of Science, School of Agriculture, Food and Ecosystem Sciences, Parkville, Victoria, Australia;
In Australia, pyrethrum (Tanacetum cinerariifolium) cultivation provides a significant portion of the global supply of natural insecticidal pyrethrins. However, crown and root rots, along with stunted plant growth and plant loss during winter, are significant issues affecting certain sites. Several isolates of the Fusarium oxysporum species complex (FOSC) have been identified as causal agents of crown and root rot in pyrethrum, highlighting these as key pathogens contributing to this decline.
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