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Monocytes maintain central nervous system homeostasis following helminth-induced inflammation.
Proc Natl Acad Sci U S A
September 2022
Center for Immunity and Inflammation, New Jersey Medical School, Rutgers, The State University of New Jersey, Newark, NJ 07103.
Article Synopsis
- Neuroimmune interactions help control how our body reacts to sickness and inflammation.
- New research shows that the brain can detect inflammation happening in the body and helps calm down immune responses to protect tissues.
- The study found that certain immune cells, called monocytes, can travel to the brain after an infection and help prevent severe reactions, keeping the brain safe even after the infection is gone.
Trichinella spiralis infection ameliorates the severity of Citrobacter rodentium-induced experimental colitis in mice.
Exp Parasitol
July 2022
College of Veterinary Medicine, Jilin Agricultural University, Changchun, China; Jilin Provincial Engineering Research Center of Animal Probiotics, Jilin Provincial Key Laboratory of Animal Microecology and Healthy Breeding, Jilin Agricultural University, Changchun, China; Key Laboratory of Animal Production and Product Quality Safety of Ministry of Education, Jilin Agricultural University, Changchun, China. Electronic address:
Trichinellosis is a food-borne zoonotic parasitic disease that causes serious harm to human health and the pig breeding industry. However, there are reports that Trichinella spiralis (T. spiralis) infection can treat autoimmune diseases, including enteritis and experimental autoimmune encephalitis (EAE).
View Article and Find Full Text PDFCentral Nervous System Involvement in Trichinellosis: A Systematic Review.
Diagnostics (Basel)
May 2021
Victor Babes University of Medicine and Pharmacy Timisoara, Eftimie Murgu Sq. No. 2, 300041 Timisoara, Romania.
We reviewed the evidence on features of central nervous system (CNS) involvement in trichinellosis, systematically searching five databases (to January 2021). We categorized clinical features based on their diagnostic value as warning signs for severe CNS infection (with outcome death) or non-specific signs (outcome improvement). They were suggestive of severe infection if they substantially raised death probability.
View Article and Find Full Text PDFEndemicity of Zoonotic Diseases in Pigs and Humans in Lowland and Upland Lao PDR: Identification of Socio-cultural Risk Factors.
PLoS Negl Trop Dis
April 2016
International Livestock Research Institute, Nairobi, Kenya.
In Lao People's Democratic Republic pigs are kept in close contact with families. Human risk of infection with pig zoonoses arises from direct contact and consumption of unsafe pig products. This cross-sectional study was conducted in Luang Prabang (north) and Savannakhet (central-south) Provinces.
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