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Does the audiogram shape influence the intracochlear recording of Electrocochleography during and after cochlear implantation?
Front Neurosci
January 2025
Department of Otorhinolaryngology, Hannover Medical School, Hanover, Germany.
During cochlear implant (CI) surgery, it is desirable to perform intraoperative measurements such as Electrocochleography (ECochG) to monitor the inner ear function and thereby to support the preservation of residual hearing. However, a significant challenge arises as the recording location of intracochlear ECochG via the CI electrode changes during electrode insertion. This study aimed to investigate the relationships between intracochlear ECochG recordings, the position of the recording contact within the cochlea relative to its anatomy, and the implications for frequency and residual hearing preservation.
View Article and Find Full Text PDFThe relationship between AutoNRT thresholds and subjective programming levels revisited.
Cochlear Implants Int
January 2025
Unit of Audiology, Department of Health and Rehabilitation, Institute of Neuroscience and Physiology, University of Gothenburg, Gothenburg, Sweden.
Objectives: The aim of this study wasto systemically examine the relationship between AutoNRT thresholds and subjective programming levels by controlling for individual subject variation, and further, to propose an alternative way to calculate the AutoNRT threshold profile for programming purposes.
Methods: The study was a prospective observational study. AutoNRT thresholds, T- and C-levels were recorded at six and twelve months after activation.
Hair cells (HCs) are essential for vestibular function, and irreversible damage to vestibular HCs in mammals is closely associated with vertigo. The stimulation of HC regeneration through exogenous gene delivery represents an ideal therapeutic approach for restoring vestibular function. Overexpression of Atoh1, Pou4f3, and Gfi1 (collectively referred to as APG) has demonstrated efficacy in promoting HC regeneration in the cochlea.
View Article and Find Full Text PDFVestibular nerve neurectomy: Functional and histopathological outcomes in the cochlea of guinea pigs.
Auris Nasus Larynx
January 2025
Otorhinolaryngology and Head and Neck Surgery Department Ain Shams University Faculty of Medicine, Egypt. Electronic address:
Objectives: Experimentally test the effect of vestibular nerve neurectomy on the function and histopathology of the cochlea.
Methods: The study was conducted on 20 normal male adult pigmented guinea pigs (Cavia porcellus). First, each animal was tested with Distortion Product Otoacoustic Emissions (DPOAEs) preoperatively then vestibular neurectomy (V.
Audiometric Outcomes of Auditory Brainstem Implantation during Vestibular Schwannoma Resection in NF2 Patients.
J Neurol Surg B Skull Base
February 2025
Department of Neurosurgery, UC San Diego Medical Center, San Diego, California, United States.
Many patients with neurofibromatosis type 2 (NF2) suffer from sensorineural hearing loss, and associated cochlear nerve compromise in NF2 patients makes auditory brainstem implant (ABI) an attractive treatment option. The long-term outcomes and benefits of the device are still being explored. A retrospective review was conducted for 11 ABI recipients at a single-institution tertiary center between November 2017 and August 2022.
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