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New insights into freshwater ascomycetes: discovery of novel species in diverse aquatic habitats.
Front Cell Infect Microbiol
January 2025
Department of Economic Plants and Biotechnology, Yunnan Key Laboratory for Wild Plant Resources, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, Yunnan, China.
During investigations of freshwater fungi in Hunan and Yunnan provinces, China, sp. nov. (Nectriaceae), sp.
View Article and Find Full Text PDFImplantation of Heparin-Conjugated Fibrin Hydrogel for Local Defects of Cartilage in Knee Osteoarthritis: A Case Report.
Int Med Case Rep J
January 2025
National Scientific Center of Traumatology and Orthopedics Named After Academician Batpenov N.D., Astana, Kazakhstan.
Background: Cartilage defects in the knee joint are areas of damage and wear to the cartilage that normally covers and protects the ends of bones. These defects occur due to sudden injuries, such as trauma or sports accidents, or due to chronic conditions, such as osteoarthritis. Cartilage acts as a shock absorber (cushion absorber), reducing the impact of mechanical stress on the joints, which helps prevent bone damage during movement.
View Article and Find Full Text PDFBio-inspired mineralized collagen scaffolds with precisely controlled gradients for the treatment of severe osteoarthritis in a male rabbit model.
Int J Biol Macromol
January 2025
State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou 730000, PR China; Gansu Engineering Research Center of Medical Collagen, Lanzhou 730000, PR China. Electronic address:
Osteoarthritis affects approximately 500 million individuals globally, with severe cases often leading to osteochondral defects. Biomimetic collagen-hydroxyapatite scaffolds have been investigated for the treatment of osteochondral defects. However, achieving precise mimicry of the intricate composition, gradient nanostructure, and biological function of native tissue remains a formidable challenge.
View Article and Find Full Text PDFFertility in transgender and gender diverse people: systematic review of the effects of gender-affirming hormones on reproductive organs and fertility.
Hum Reprod Update
January 2025
Amsterdam UMC, Location Vrije Universiteit Amsterdam, Centre of Expertise on Gender Dysphoria, Amsterdam, The Netherlands.
Background: Transgender and gender diverse (TGD) people seek gender-affirming care at any age to manage gender identities or expressions that differ from their birth gender. Gender-affirming hormone treatment (GAHT) and gender-affirming surgery may alter reproductive function and/or anatomy, limiting future reproductive options to varying degrees, if individuals desire to either give birth or become a biological parent.
Objective And Rationale: TGD people increasingly pursue help for their reproductive questions, including fertility, fertility preservation, active desire for children, and future options.
Unicentric Castleman's disease (UCD) typically presents as an asymptomatic tumour in the anterior or middle mediastinum. Occurrence in the paravertebral region is comparatively rare and it requires differentiation from neurogenic tumours by imaging. In our patient, preoperative imaging findings were atypical of schwannoma.
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