Calcification of the gallbladder ("porcelain gallbladder").

Am J Roentgenol Radium Ther Nucl Med

Published: April 1963

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Article Synopsis
  • Porcelain gallbladder is a rare condition marked by calcification of the gallbladder wall, increasing the risk of gallbladder cancer and leading to high levels of the tumor marker CA19-9.
  • A case study presented a 60-year-old woman with abdominal pain and nausea, where imaging revealed porcelain gallbladder and common bile duct stones; her CA19-9 levels were extremely elevated after stone removal.
  • Post-surgery, histopathology showed no cancer but inflammation and calcification, and CA19-9 levels normalized, emphasizing that benign conditions can elevate CA19-9 and the importance of accurate diagnosis.
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Background: Liposarcoma (LPS) is a kind of malignancy of soft tissue usually found in the retroperitoneal, limb, or neck region, and some may be detected with delayed symptoms (pain or palpable mass), and less frequently occurs in organs of the digestive system. In contrast, Dedifferentiated liposarcoma (DDLPS) is a common histological subtype of LPS. The present study reported a case of dedifferentiated liposarcoma originating in the gallbladder.

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Commonly referred to as a "porcelain gallbladder (PGB)," gallbladder calcification is usually asymptomatic. It is observed that chronic inflammation of the gallbladder can occur as a result of another underlying condition, specifically gallstone disease. In the past, there was a belief that PGB had a correlation with gallbladder cancer, with an incidence rate of 30%.

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An Intriguing Case of Myocardial Deposits.

Cureus

August 2024

Advanced Cardiac Imaging, Willis Knighton Health, Shreveport, USA.

Cardiac calcification refers to calcium deposits in the coronary arteries, heart valves, pericardium, or myocardium. Calcium deposition within the myocardium is unique and can be secondary to metastatic or dystrophic calcification. Both forms are linked to cardiac abnormalities and poor prognosis.

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Gallbladder disorders encompass a spectrum from congenital anomalies to inflammatory and neoplastic conditions, frequently requiring surgical intervention. Epithelial abnormalities like adenoma and metaplasia have the potential to progress to carcinoma, emphasizing the importance of histopathological assessment for early detection of malignancy. Gallbladder cancer (GBC) may be incidentally discovered during cholecystectomy for presumed benign conditions, underscoring the need for a thorough examination.

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