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[Association between prescription of long-term systemic glucocorticoid therapy associated measures and prescriber's medical speciality].
Rev Med Interne
July 2019
Service de dermatologie, hôpital Henri-Mondor, 94000 Créteil, France; Équipe d'accueil EA7379 EpiDermE, université Paris-Est Créteil, 94000 Créteil, France.
Introduction: In order to prevent some glucocorticoid-induced adverse events, adjuvant measures are often associated with prescription of long-term (≥3 months) systemic glucocorticoid therapy. The main objective of this study was to study the association between prescription of these measures and the medical specialty of the prescriber.
Methods: A cross-sectional study was conducted through the website www.
[Naming and classification of steroids and human stress ulcers. Articles of historic significance published by Hans Selye 70 years ago].
Orv Hetil
August 2015
Departments of Pathology and Pharmacology, University of California-Irvine, School of Medicine Health Sci. Rd., Irvine, CA 92697, USA.
The name of Hans Selye is mostly known worldwide as the discoverer of stress reaction. Yet, he made numerous other seminal and clinically relevant discoveries. Namely, since he had a focused research on steroid hormones originating from the adrenal cortex that play a crucial role in stress response, he was the first who introduced about 70 years ago the first classification of steroids that is still valid nowadays.
View Article and Find Full Text PDFPoor late prognosis of bleeding peptic ulcer.
Langenbecks Arch Surg
September 2007
Department of General and Trauma Surgery, Malteser Hospital St. Hildegardis, Cologne, Germany.
Background And Aims: Long-term course of peptic ulcer bleeding is unclear. Because of a more aged and more diseased ulcer population, the long-term prognosis may be expected as poor.
Materials And Methods: In a prospective study, all patients with peptic ulcer bleeding treated at the Department of Surgery of the Heinrich-Heine-University in Düsseldorf were included between 1986 and 1995.
Imunosuppression by a corticosteroid fails to exacerbate Helicobacter pylori infection in a mouse model of gastric colonization.
Can J Microbiol
November 1999
National Research Council Canada, Institute for Biological Sciences, Ottawa, Canada.
Helicobacter pylori can colonize the human stomach for prolonged periods of time, and this colonization uniformly leads to the development of chronic active gastritis. In a small percentage of individuals, gastric pathology progresses to peptic ulceration or more rarely certain gastric cancers. In addition to non-specific inflammation, specific systemic and local immunity develops in response to gastric colonization by this pathogen.
View Article and Find Full Text PDFRadiotherapy without steroids in selected metastatic spinal cord compression patients. A phase II trial.
Am J Clin Oncol
April 1996
Department of Radiation Oncology, Policlinico Monteluce, Perugia, Italy.
A phase II trial was planned to investigate the feasibility of radiotherapy (RT) without steroids in 20 consecutive patients with metastatic spinal cord compression (MSCC), no neurologic deficits, or only radiculopathy, and no massive invasion of the spine at magnetic resonance imaging (MRI) or computed tomography (CT). Aiming at an early diagnosis, MRI or CT was prescribed for all cancer patients with back pain and osteolysis, even when there were no signs of neurologic spinal compression. All patients were given 30 Gy in 10 fractions over 2 weeks with no steroids.
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