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A comparative study on the antipyretic effect and underlying mechanisms of different bile-fermented Arisaemas.
J Ethnopharmacol
January 2025
Key Laboratory of Basic and Application Research of Beiyao (Heilongjiang University of Chinese Medicine), Ministry of Education, 24 Heping Road, Xiangfang District, Harbin, 150040, China; School of Traditional Chinese Medicine, Guangdong Pharmaceutical University, Guangzhou, 510006, China. Electronic address:
Ethnopharmacological Relevance: Cattle bile Arisaema (CBA) and Pig bile Arisaema (PBA) are both processed products fermented from Arisaema erubescens (Wall.) Schott and animal bile, which are recorded in China Pharmacopoeia. Traditionally, bile Arisaema was often used for clearing heat and eliminating phlegm, calming wind and calming panic.
View Article and Find Full Text PDFInsights about levels and sources of organic pollution in an urbanized Amazon estuary (Belém, PA, Northern Brazil).
Environ Monit Assess
May 2023
Federal University of Pará, Rua Augusto Corrêa, 1 - Guamá,, Belém, PA, 66075-110, Brazil.
Amazon aquatic systems have been affected by organic pollution from urbanized regions. This study was conducted to determine the levels, sources, and distribution patterns of 16 polycyclic aromatic hydrocarbons (PAHs) and 6 steroid markers in surficial sediments from an important urbanized Amazon estuarine system (Belém, PA, Northern Brazil). Total PAH concentration (∑PAH) ranged from 878.
View Article and Find Full Text PDFMicrobial and Host Metabolites at the Backstage of Fever: Current Knowledge about the Co-Ordinate Action of Receptors and Molecules Underlying Pathophysiology and Clinical Implications.
Metabolites
March 2023
Interdisciplinary Department of Medicine, Section of Microbiology and Virology, School of Medicine, University of Bari 'Aldo Moro', 70124 Bari, Italy.
Fever represents an elevation of body temperature, that exerts a protective effect against pathogens. Innate immune cells and neurons are implicated in the regulation of body temperature. Pathogen-associated molecular patterns, i.
View Article and Find Full Text PDFEffects of sub-chronic oral exposure to pyrogenic synthetic amorphous silica (NM-203) in male and female Sprague-Dawley rats: focus on reproductive systems.
Reprod Toxicol
October 2021
Center for Gender-Specific Medicine, Istituto Superiore di Sanità (ISS), Viale Regina Elena 299, Rome, Italy. Electronic address:
Synthetic amorphous silica (SAS) consists of agglomerates and aggregates of primary particles in the nanorange (<100 nm) and it is the E551 authorized food additive. The potential risks for human health associated to dietary exposure to SAS are not completely assessed; in particular, data on male and female reproductive systems are lacking. A 90-day oral toxicity study with pyrogenic SAS nanomaterial NM-203 was carried out on the basis of the OECD test guideline 408 in the frame of the NANoREG project.
View Article and Find Full Text PDFThe efficacy of steroids in reducing morbidity and mortality from extreme hyperthermia and heatstroke-A systematic review.
Pharmacol Res Perspect
August 2020
Division of Sport, Health and Exercise Sciences, Centre for Human Performance, Exercise and Rehabilitation (CHPER), Brunel University London, Uxbridge, UK.
Severe hyperthermia from classical or exertional heatstroke, or from drug ingestion or other noninfective pyrogens, is associated with a high mortality and morbidity. A systemic pro-inflammatory response occurs during heatstroke, characterized by elevated cytokines with endotoxemia from elevated lipopolysaccharide (LPS) levels. Corticosteroids reduce LPS and cytokine levels, suggesting that they may improve outcome.
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