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Cornea
January 2025
Instituto de Oftalmologia Fundacion Conde de Valenciana IAP, Mexico City, Mexico.
Purpose: To report the surgical management and outcomes of a patient with granulomatous inflammation following scleral tattooing, emphasizing the associated risks and clinical implications.
Methods: A 26-year-old woman with a history of multiple body modifications, including scleral tattooing, presented with bilateral ocular pain and discomfort. Clinical examination revealed corneal dellen and subconjunctival granulomas.
Cureus
December 2024
Emergency Medicine, Whittington Health NHS Trust, London, GBR.
Introduction Ophthalmology presentations contribute significantly to Accident and Emergency (A&E) attendance. The provision of safe care depends on clinical skills and appropriate equipment. This quality improvement project aimed to increase the availability of ophthalmoscopes and Snellen charts required for a basic ophthalmological assessment in an A&E department in North London.
View Article and Find Full Text PDFPsychol Res Behav Manag
January 2025
Department of Ophthalmology, Tianjin Medical University General Hospital, Tianjin, 300052, People's Republic of China.
Purpose: The present study aimed to investigate the prevalence of anxiety and depression in patients with mechanical ocular injuries, and the effects of worry and resilience on anxiety and depression.
Patients And Methods: Patients with one eye of mechanical ocular injuries and healthy residents were recruited from June 8, 2022, to March 1, 2023. All subjects participated in psychologically relevant questionnaires including the Self-rating Anxiety Scale(SAS), the Self-rating Depression Scale(SDS), the Connor- Davidson Resilience Scale (CD-RISC), and the Penn State Worry Questionnaire(PSWQ).
Biomater Sci
January 2025
Department of Chemical Engineering, University of Waterloo, 200 University Avenue West, Waterloo, ON N2L 3G1, Canada.
The treatment of corneal blindness due to corneal diseases and injuries often requires the transplantation of healthy cadaveric corneal endothelial graft tissue to restore corneal clarity and visual function. However, the limited availability of donor corneas poses a significant challenge in meeting the demand for corneal transplantation. As a result, there is a growing interest in developing strategies alleviate this unmet need, and one of the postulated approaches is to isolate and expand primary human corneal endothelial cells (HCECs) for use in cell therapy.
View Article and Find Full Text PDFIran J Pharm Res
September 2024
Chemical Injuries Research Center, Systems Biology and Poisonings Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran.
Background: Dry eye disease (DED) is a multifactorial condition characterized by ocular surface inflammation, tear film instability, and corneal epithelial damage. Current treatments often provide temporary relief without addressing the underlying inflammatory mechanisms.
Objectives: This study examined the therapeutic potential of crocin and nobiletin, two naturally derived compounds with well-known antioxidant and anti-inflammatory properties, in a mouse model of DED induced by lacrimal gland excision (LGE).
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