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Severe pregnancy-associated atypical hemolytic uremia syndrome in the context of the COVID-19 pandemic: a novel survival case report.
BMC Pregnancy Childbirth
January 2025
Department of Intensive Care Medicine, Army Medical Center of PLA, No. 10 Changjiang Road, Yuzhong District, Chongqing, 400010, People's Republic of China.
Background: Pregnancy-associated atypical hemolytic uremic syndrome (aHUS) is a form of thrombotic microangiopathy (TMA) caused by uncontrolled activation of the complement system during pregnancy or the postpartum period. In the intensive care unit, aHUS must be differentiated from sepsis-related multiple organ dysfunction, thrombotic thrombocytopenic purpura (TTP), hemolysis, elevated liver enzymes, and low platelet (HELLP) syndrome. Early recognition of aHUS is critical for effective treatment and improved prognosis.
View Article and Find Full Text PDFAssociation between cardiovascular health and osteoporotic fractures: a national population-based study.
Sci Rep
January 2025
Department of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University, NO. 172 Tong Zi Po Road, Yuelu District, Changsha, 410006, Hunan, China.
Osteoporotic fractures are a major public health concern, particularly among the aging population, as they significantly contribute to morbidity, mortality, and reduced quality of life. While cardiovascular health (CVH) has traditionally been linked to cardiovascular disease outcomes, emerging evidence suggests it may also influence bone health. This study investigates the association between CVH, as measured by the Life's Essential 8 (LE8) score, and the prevalence of osteoporotic fractures in U.
View Article and Find Full Text PDFImproving UK data on avoidable perinatal brain injury: review of data dictionaries and consultation.
Pediatr Res
January 2025
THIS Institute (The Healthcare Improvement Studies Institute), University of Cambridge, Strangeways Research Laboratory, Cambridge, CB1 8RN, UK.
Background: High quality data is important to understanding epidemiology and supporting improvement efforts in perinatal brain injury. It is not clear which data items relevant to brain injury are captured across UK sources of routinely collected data, nor what needs to be done to ensure that those sources are fit for purpose in improving care.
Methods: We reviewed data dictionaries of four main UK perinatal data sources and consulted a multi-professional group (N = 27) with expertise in neonatal/maternity care, statistics, and clinical negligence.
Stress Cardiac Magnetic Resonance Imaging in Intermediate-Risk Emergency Department Patients with Abnormal High-Sensitivity Troponin.
J Cardiovasc Magn Reson
January 2025
Duke University School of Medicine, Department of Medicine, 2301 Erwin Road, Durham, NC 27710 Durham, NC; Duke University Cardiovascular Magnetic Resonance Center, 2301 Erwin Road, Durham, NC 27710 Durham, NC. Electronic address:
Background: Patients presenting to the emergency department (ED) with chest pain often have abnormal high-sensitivity troponin (hsTn). However, only about 5% have an acute coronary syndrome. We aimed to assess the safety, feasibility and utility of a clinical disposition protocol including outpatient observation with stress cardiac-magnetic-resonance (CMR) in intermediate-risk patients with abnormal hsTn of unclear etiology.
View Article and Find Full Text PDFEffects of Prophylactic Coil Embolization of Pelvic Arteries on Surgical Outcomes in Hemodynamically Stable Patients with Complex Acetabular Fractures.
J Vasc Interv Radiol
January 2025
Department of Radiology; Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine; No. 600, Yishan Road; Shanghai, 200233, China. Electronic address:
Objectives: To investigate the efficacy of prophylactic embolization of the internal iliac artery (IIA) or superior gluteal artery (SGA) before open reduction and internal fixation (ORIF) in reducing intraoperative blood loss (IBL) in hemodynamically stable patients with complex acetabular fractures.
Materials And Methods: A total of 136 patients with complex acetabular fractures were retrospectively included and divided into the prophylactic transcatheter arterial embolization (PTAE) group and non-PTAE group, depending on whether ipsilateral IIA or SGA was embolized using coils within 3 days before ORIF. Demographic characteristics, injury severity score (ISS), fracture classification, and intraoperative and postoperative data were compared between the two groups.
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