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Construction of a multifunctional bio-probe based on lanthanides for UCL/MR/CT multimodal imaging.
Biomed Mater
January 2025
Department of Interventional Therapy, The First Affliated Hospital of Wannan Medical College (Yijishan Hospital of Wannan Medical College), Wuhu, People's Republic of China.
Multimodal bioimaging is beneficial for clinical diagnosis and research due to the provision of comprehensive diagnostic information. However, the design of multifunctional bio-probes aggregating multiple bioimaging functions is greatly challenging. In this study, a multifunctional bio-probe based on lanthanide-based nanomaterials SrGdF: Yb/Er/Tm(abbreviated as SGF) was developed formultimodal imaging by co-adopting apropos lanthanides and tuning their molar ratio.
View Article and Find Full Text PDFQuality of Life of Breast Cancer Women under Treatment at a Tertiary Care Center of Western Maharashtra.
Indian J Community Med
October 2024
Medical Oncology Army Hospital Research and Referral, Delhi, India.
Background: 'Breast cancer' the most common cancer amongst females in India. Having good Quality of life (QoL) among the patients undergoing treatment is one of the vital and significant factors for ensuring holistic approach to treatment and well-being of cancer patients. The present study was conducted to assess the QoL and its determinants among breast cancer patients undergoing treatment at a tertiary care institute in western Maharashtra.
View Article and Find Full Text PDFCytotoxic evaluation of pure and doped iron oxide nanoparticles on cancer cells: a magnetic fluid hyperthermia perspective.
Nanotoxicology
August 2024
Dr. K C Patel Research and Development Centre, University Research Centre(s), Charotar University of Science and Technology (CHARUSAT), Changa, India.
The need of the hour with respect to cancer treatment is a targeted approach with minimal or nil ramifications. Apropos, magnetic fluid hyperthermia (MFH) is emerging as a potential therapeutic strategy with anticipated reduced side effects for solid tumors. MFH causes cytotoxicity due to the heat generated owing to Hysteresis, Neel, and Brownian relaxation losses once magnetic nanoparticles (MNPs) carrying cancer cells are placed under an alternating magnetic field.
View Article and Find Full Text PDFImmune checkpoint inhibitors-associated thrombosis in patients with head and neck cancer: a study of the Spanish society of medical oncology (SEOM) thrombosis and cancer group.
Clin Transl Oncol
January 2025
Spanish Society of Medical Oncology (SEOM) Thrombosis and Cancer Group, Madrid, Spain.
Purpose: Both venous and arterial thrombotic events (VTE/AT) can be associated with Immune Checkpoint Inhibitors (ICI). However, there is a paucity of information apropos patients in routine clinical practice.
Methods: /Patients.
Lyophilised protein formulations as a patient-centric dosage form: A contribution toward sustainability paradigm.
Acta Pharm
June 2024
1University of Ljubljana, Faculty of Pharmacy, Department of Pharmaceutical Technology, 1000 Ljubljana, Slovenia.
Article Synopsis
- - Society is focusing on the need for innovative pharmaceutical technologies to address challenges like population aging and climate change, particularly targeting patient-specific drug delivery systems.
- - The development of protein drugs for subcutaneous administration is crucial but faces challenges such as maintaining protein stability and appropriate formulation viscosity during manufacturing.
- - A study using bovine serum albumin explored how protein concentration impacts the quality of liquid and lyophilized formulations, confirming that higher concentrations lead to increased viscosity and longer reconstitution times, while identifying the critical role of sucrose and the need to balance it with mannitol in lyophilization.
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