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Investigating the significance of SPECT/CT-SUV for monitoring Lu-PSMA-targeted radionuclide therapy: a systematic review.
BMC Med Imaging
January 2025
Department of Radiological Sciences, College of Health and Rehabilitation Sciences, Princess Nourah Bint Abdulrahman University, P.O. Box 84428, Riyadh, 11671, Saudi Arabia.
Background: Quantitative molecular imaging via single-photon emission computed tomography-derived standardised uptake value (SPECT/CT-SUV) is used to assess the response of metastatic castration-resistant prostate cancer (mCRPC) patients to targeted radionuclide therapy (TRT) with [Lu]Lu-PSMA. This imaging technique determines the radiopharmaceutical distribution and internal dosimetry in patients who receive TRT. However, there is limited evidence regarding the role of image quantification in monitoring changes induced by [Lu]Lu-PSMA.
View Article and Find Full Text PDFEffective doses received by the gastrointestinal tract compartments of adults due to food intake in Egypt.
Sci Rep
January 2025
Faculty of Computer and Information, South Valley University, Qena, 83523, Egypt.
Ra, Th, and K levels in various foods frequently consumed by Egyptians were determined using a gamma-ray spectrometer based on the germanium detector (HPGe). Activity concentrations of Ra, Th, and K were in the range of < 0.10 to 0.
View Article and Find Full Text PDFPreclinical evaluation and preliminary clinical study of Ga-NODAGA-NM-01 for PET imaging of PD-L1 expression.
Cancer Imaging
January 2025
Department of Nuclear Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Hongkou District, No. 100, Haining Road, Shanghai, 200080, China.
Background: Programmed cell death 1/programmed death ligand-1 (PD-L1)-based immune checkpoint blockade is an effective treatment approach for non-small-cell lung cancer (NSCLC). However, immunohistochemistry does not accurately or dynamically reflect PD-L1 expression owing to its spatiotemporal heterogeneity. Herein, we assessed the feasibility of using a Ga-labeled anti-PD-L1 nanobody, Ga-NODAGA-NM-01, for PET imaging of PD-L1.
View Article and Find Full Text PDFPhysical, chemical and biological properties of MTA Angelus and novel AGM MTA: an in vitro analysis.
BMC Oral Health
January 2025
School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Introduction: Mineral trioxide aggregate (MTA) is a calcium silicate-based cement that has changed conventional dental therapeutic approaches. This study aimed to evaluate physical, chemical and biological properties of novel AGM MTA, in comparison with MTA Angelus.
Methods: The samples were prepared according to the manufacturer's instructions.
Fuzzy logic modelling of the pollution pattern of potentially toxic elements and naturally occurring radionuclide materials in quarry sites in Ogun State, Nigeria.
Environ Geochem Health
January 2025
Department of Chemistry, Chulalongkorn University, Bangkok, Thailand.
The accumulation pattern of some inorganic pollutants in quarry sites around Ogun State was modeled using a Fuzzy comprehensive assessment (FCA). Potentially toxic elements (PTEs) and naturally occurring radionuclides materials (NORMs) were assessed from soil samples collected from ten quarry sites in three districts (Odeda, Ajebo, and Ijebu Ode) in Ogun State. Three (3) NORMs ( K, U, Th) were assessed using gamma spectrometer with a NaI detector while ten (10) PTEs (As, Cd, Co, Cr, Cu, Fe, Mn, Ni, Pb, and Zn) were determined by digestion method using Inductively coupled plasma optical emission spectrophotometer.
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