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Introduction: Collision tumors of the appendix are rare tumors consisting of two distinct pathologies arising from different cell lines simultaneously. The most common type is the coexistence of a neuroendocrine tumor (NET) with a low-grade appendiceal mucinous neoplasm (LAMN). We report a unique case of appendiceal collision tumor with synchronous cecal intra-mucosal carcinoma and pulmonary sarcoidosis.

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Subhepatic appendicitis is an unusual presentation of acute appendicitis (AA). Similarly, another uncommon condition that resembles AA is appendiceal diverticulitis (AD), which is a rare form of vermiform appendix pathology. It is exceedingly uncommon for the two to occur simultaneously.

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We present a case of multiple abdominal pathologies occurring simultaneously, which emphasizes the importance of keeping a broad differential and evaluating each diagnosis. A 33-year-old female presented with abdominal pain, nausea, and vomiting. Her workup included computerized tomography which demonstrated acute appendicitis with concern for a closed-loop bowel obstruction.

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The prediction of the coexistence of acute appendicitis and renal colic can be challenging, especially when the patient's symptoms point toward one diagnosis. In this case report, we describe a patient who presented to the emergency department with severe lower abdominal pain that was thought to be solely due to acute appendicitis. Further evaluation, however, revealed the simultaneous coexistence of a right ureteral stone, causing severe hydroureteronephrosis.

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Article Synopsis
  • Severe infections can cause immune cells to overreact, leading to lasting organ damage, while anti-inflammatory drugs may increase infection risks instead of helping.
  • A new nanomedicine using nanoparticles loaded with a photosensitizer and a chemiluminescent agent targets an inflammatory environment to effectively kill pathogens and overactive immune cells.
  • This innovative approach has shown significant success in various infection models, suggesting these nanoparticles could be a promising treatment option for severe infectious diseases by balancing infection control and inflammation reduction.
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