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Myocardial Flow Assessment After Heart Transplantation Using Dynamic Cadmium-Zinc-Telluride Single-Photon Emission Computed Tomography With Tl and Tc Tracers and Validated by N-NH Positron Emission Tomography.
Circ Cardiovasc Imaging
June 2023
Institute of Environmental and Occupational Health Sciences (M.-F.C.), National Taiwan University, Taipei.
Background: Cardiac allograft vasculopathy (CAV) is an obliterative and diffuse form of vasculopathy and is the most common cause of long-term cardiovascular mortality in heart transplant patients. This study aimed to investigate the diagnostic performance of Tc and Tl tracers in the assessment of CAV using cadmium-zinc-telluride (CZT) single-photon emission computed tomography (SPECT) for myocardial blood flow (MBF) and myocardial flow reserve (MFR) quantification, which was further validated using N-NH positron emission tomography (PET).
Methods: Thirty-eight patients with prior heart transplantation who underwent CZT SPECT and N-NH PET dynamic scans were included in this study.
The role of non-invasive imaging modalities in cardiac allograft vasculopathy: an updated focus on current evidences.
Heart Fail Rev
July 2022
Department of Medical Biotechnologies, Section of Cardiology, University of Siena, Siena, Italy.
Cardiac allograft vasculopathy (CAV) is an obliterative and diffuse form of vasculopathy affecting almost 50% of patients after 10 years from heart transplant and represents the most common cause of long-term cardiovascular mortality among heart transplant recipients. The gold standard diagnostic technique is still invasive coronary angiography, which however holds potential for complications, especially contrast-related kidney injury and procedure-related vascular lesions. Non-invasive and contrast-sparing imaging techniques have been advocated and investigated over the past decades, in order to identify those that could replace coronary angiography or at least reach comparable accuracy in CAV detection.
View Article and Find Full Text PDFPathologic Disparities Between Peripheral Artery Disease and Coronary Artery Disease.
Arterioscler Thromb Vasc Biol
September 2020
Department of Pathology, New York University Grossman School of Medicine, New York, NY (Navneet Narula).
Atherosclerosis is a systemic disease that involves multiple vascular beds. The pathological characteristics and clinical presentation, however, vary among the different vascular territories. Acute coronary syndrome is a relatively common manifestation of coronary atherosclerotic disease, wherein the thrombosis occurs secondary to disruption (65%-75%) and erosion (25%-35%) of the fibrous caps of atheromatous plaques.
View Article and Find Full Text PDFRadiation dose and image quality with new protocol in lower extremity computed tomography angiography.
Radiol Med
March 2019
Department of Radiology, Azienda Ospedaliero-Universitaria, Ospedali Riuniti di Ancona, Via Conca 71, 60126, Torrette, Ancona, Italy.
Purpose: To compare radiation dose and image quality of lower extremity computed tomography angiography (CTA) between cranio-caudal acquisition with single-source CT (SSCT) and flash caudo-cranial acquisition with dual-source CT (DSCT).
Materials And Methods: In this prospective study, 60 patients were randomly assigned to Group A (control) or Group B (experimental) to undergo lower extremity CTA for peripheral obliterative arterial disease. Group A received protocol 1 (P1) with SSCT cranio-caudal acquisition.
[Atypical and revelatory livedo reticularis!?].
Pan Afr Med J
June 2018
Department of Dermatology-Venereology, Military Training Hospital Mohammed V, Rabat, Morocco.
Atherosclerosis is a frequent and life-threatening complication in elderly patients with multimorbidity as well as with one or multiple cardiovascular risk factors. It can affect all the arterial trunks of the lower limbs and can cause obliterative arterial disease of the lower limbs. We here report the case of an elderly patient with ecchymotic livedo reticularis of the right thigh revealing ipsilateral obliterative arterial disease of the lower limb with septic loosening of total hip prosthesis.
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