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Microplastic Migration and Transformation Pathways and Exposure Health Risks.

Environ Pollut

January 2025

Department of Pathology and Laboratory Medicine, The University of Kansas Medical Center, Kansas City, KS 66160, USA. Electronic address:

Plastics play a crucial role in modern life, but improper use and disposal have resulted in microplastics becoming widespread in the environment, raising significant concerns about both the environment and human health. Extensive research has explored the transformation mechanisms, bioaccumulation, ecological impacts, and health risks associated with microplastics. The present review first analyzes the migration, transformation, and degradation pathways of microplastics on a global scale, and then synthesizes current knowledge on the types, sources, and migration pathways of microplastics in soil, atmosphere, and aquatic environments, emphasizing transformation mechanisms like photo-aging and microbial degradation, and detailing their ecological and human health impacts.

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Introduction:   The entrance of Generation Z (born 1997-2012) into professional life, including the practice of medicine, marks a transformational shift in priorities and values. This generation, shaped by digital immersion and a strong focus on work-life balance, is redefining the landscape of Plastic Surgery. Their preferences for inclusivity, innovation, and structured working hours challenge traditional models of mentorship, patient care, and surgical training.

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Environmental Enrichment and Epigenetic Changes in the Brain: From the Outside to the Deep Inside.

Subcell Biochem

January 2025

Facultad de Medicina y Ciencia, Universidad San Sebastián, Santiago, Chile.

The brain plays a vital role in maintaining homeostasis and effective interaction with the environment, shaped by genetic and environmental factors throughout neurodevelopment and maturity. While genetic components dictate initial neurodevelopment stages, epigenetics-specifically neuroepigenetics-modulates gene expression in response to environmental influences, allowing for brain adaptability and plasticity. This interplay is particularly evident in neuropathologies like Rett syndrome and CDKL5 deficiency syndrome, where disruptions in neuroepigenetic processes underline significant cognitive and motor impairments.

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Impact of leachate from boiled-water-treated plastic products on male reproductive health: Insights from transcriptomic and metabolomic profiling.

Ecotoxicol Environ Saf

January 2025

Department of Urology & Andrology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310016, China. Electronic address:

Given the extensive use of plastic materials in modern society, there is an escalating concern about the potential risks associated with exposure to plastic products. This study investigated the impact of plastic leachates from boiled-water-treated cups, including polypropylene (PP), high-density polyethylene (HDPE), low-density polyethylene (LDPE), polystyrene (PS), and polyethylene terephthalate (PET), on male reproductive health. Experimental mice were administered daily doses of the plastic leachates for 180 consecutive days.

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