This paper offers a brief review of the issues related to selection of the polymeric matrix base that determines the possibilities of forming medicinal film. Estimated is its efficiency as compared to other polymeric carriers. Also discussed are examples of using medicinal films in certain fields of medicine.
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Front Oncol
December 2024
Institute of Radiation Medicine (IRM), Helmholtz Zentrum München GmbH, German Research Center for Environmental Health, Neuherberg, Germany.
PLoS One
December 2024
Division of Ophthalmology, Department of Special Surgery, Faculty of Medicine, Jordan University of Science & Technology, Irbid, Jordan.
Purpose: The emulsification of silicone oil (SO) remains poorly understood. In the present study, we investigated the physical properties of unused pharmaceutical SO samples under various conditions. Moreover, clinical correlations with the patients' SO samples were assessed.
View Article and Find Full Text PDFMembranes (Basel)
December 2024
Department of Physical Chemistry, Faculty of Chemistry and Pharmacy, Sofia University St. Kliment Ohridski, 1 "James Bourchier" Blvd., 1164 Sofia, Bulgaria.
Poly(butyl cyanoacrylate) (PBCA) nanoparticles have numerous applications, including drug and gene delivery, molecular imaging, and cancer therapy. To uncover the molecular mechanisms underlying their interactions with cell membranes, we utilized a Langmuir monolayer as a model membrane system. This approach enabled us to investigate the processes of penetration and reorganization of PBCA nanoparticles when deposited in a phospholipid monolayer subphase.
View Article and Find Full Text PDFNanomaterials (Basel)
December 2024
Department of Biomedical Engineering, City University of Hong Kong, 83 Tat Chee Avenue, Kowloon, Hong Kong 999077, China.
Multiplexed biosensing methods for simultaneously detecting multiple biomolecules are important for investigating biological mechanisms associated with physiological processes, developing applications in life sciences, and conducting medical tests. The development of biosensors, especially those advanced biosensors with multiplexing potentials, strongly depends on advancements in nanotechnologies, including the nano-coating of thin films, micro-nano 3D structures, and nanotags for signal generation. Surface functionalization is a critical process for biosensing applications, one which enables the immobilization of biological probes or other structures that assist in the capturing of biomolecules.
View Article and Find Full Text PDFGels
November 2024
Biopolymer Research & Engineering Laboratory (BIOPREL), Escuela de Nutrición y Dietética, Facultad de Medicina, Universidad de Los Andes, Santiago 7550000, Chile.
Gelatin is a natural hydrocolloid with excellent film-forming properties, high processability, and tremendous potential in the field of edible coatings and food packaging. However, its reinforcing by materials such as cellulose nanocrystals (CNC) is often necessary to improve its mechanical behavior, including shape memory properties. Since the interaction between these polymers is complex and its mechanism still remains unclear, this work aimed to study the effect of low concentrations of CNC (2, 6, and 10 weight%) on the molecular organization, thermomechanical, and shape memory properties in mammalian gelatin-based composite films at low moisture content (~10 weight% dry base).
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