Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/0006-3002(62)90962-9 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Investigations of Long-Acting Formulations in Children, Adolescents, and Pregnant Women: A Systematic Review.
Pharmaceutics
January 2025
Division of Clinical Pharmacology, Department of Medicine, School of Medicine, The Johns Hopkins University, Baltimore, MD 21287, USA.
Long-acting and extended-release drug delivery strategies have greatly improved treatment for a variety of medical conditions. Special populations, specifically infants, children, young people, and pregnant and postpartum women, could greatly benefit from access to these strategies but are often excluded from clinical trials. We conducted a systematic review of all clinical studies involving the use of a long-acting intramuscular injection or implant in infants, children, young people, and pregnant and postpartum people.
View Article and Find Full Text PDFBatch-to-Batch Variation and Patient Heterogeneity in Thymoglobulin Binding and Specificity: One Size Does Not Fit All.
J Clin Med
January 2025
Department of Internal Medicine, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.
Thymoglobulin is used to prevent allograft rejection and is being explored at low doses as intervention immunotherapy in type 1 diabetes. Thymoglobulin consists of a diverse pool of rabbit antibodies directed against many different targets on human thymocytes that can also be expressed by other leukocytes. Since Thymoglobulin is generated by injecting rabbits with human thymocytes, this conceivably leads to differences between Thymoglobulin batches.
View Article and Find Full Text PDFNumerical Study to Analyze the Influence of Process Parameters on Temperature and Stress Field in Powder Bed Fusion of Ti-6Al-4V.
Materials (Basel)
January 2025
Department of Industrial Engineering, University of Salerno, 84084 Fisciano, SA, Italy.
This paper presents a comprehensive numerical investigation to simulate heat transfer and residual stress formation of Ti-6Al-4V alloy during the Laser Powder Bed Fusion process, using a finite element model (FEM). The FEM was developed with a focus on the effects of key process parameters, including laser scanning velocity, laser power, hatch space, and scanning pattern in single-layer scanning. The model was validated against experimental data, demonstrating good agreement in terms of temperature profiles and melt pool dimensions.
View Article and Find Full Text PDFComprehensive evaluation of lifespan-extending molecules in C. elegans.
Aging Cell
January 2025
EPITERNA, Epalinges, Switzerland.
The nematode C. elegans has long served as a gold-standard model organism in aging research, particularly since the discovery of long-lived mutants in conserved aging pathways including daf-2 (IGF1) and age-1 (PI3K). Its short lifespan and small size make it highly suitable for high-throughput experiments.
View Article and Find Full Text PDFPost-Vaccination Anaphylaxis in Adults: A Systematic Review and Meta-Analysis.
Vaccines (Basel)
January 2025
School of Medicine, Università Vita-Salute San Raffaele, 20132 Milan, Italy.
Background/objectives: Vaccines have been recognized as one of the most effective public health interventions. However, vaccine-associated anaphylaxis, although rare, is a serious adverse reaction. The incidence of anaphylaxis related to non-COVID-19 vaccines in adults remains underreported.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!