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Pessary or cerclage (PC study) to prevent recurrent preterm birth: a non-inferiority, randomised controlled trial.
EClinicalMedicine
December 2024
Department of Obstetrics and Gynaecology, Amsterdam UMC Location University of Amsterdam, Meibergdreef 9, Amsterdam, the Netherlands.
Background: Previous spontaneous preterm birth (sPTB) is a strong risk indicator for recurrent preterm birth (PTB). Cervical cerclage is an accepted intervention to prevent recurrent PTB in high risk patients. Cervical pessary might be a less invasive alternative.
View Article and Find Full Text PDFCervical cell's nucleus segmentation through an improved UNet architecture.
PLoS One
October 2023
Department of Computer Science & Information Technology, Hazara University Mansehra, Mansehra, Pakistan.
Precise segmentation of the nucleus is vital for computer-aided diagnosis (CAD) in cervical cytology. Automated delineation of the cervical nucleus has notorious challenges due to clumped cells, color variation, noise, and fuzzy boundaries. Due to its standout performance in medical image analysis, deep learning has gained attention from other techniques.
View Article and Find Full Text PDFI W Rowlands, Barbara J Weir and the biology of the hystricomorph rodents.
Reproduction
July 2023
Laboratory of Histology and Embryology Descriptive, Experimental and Comparative, School of Veterinary Sciences, National University of La Plata, CONICET, Buenos Aires, Argentina.
In Brief: Current research on the genomics, ecology and reproductive biology of hystricomorph rodents relies on the pioneering studies of B J Weir and I W Rowlands. We show the enduring influence of a symposium on hystricomorph biology held 50 years ago.
Abstract: The rodent suborder Hystricomorpha comprises seven families from Africa and Asia and ten from South America, where they have undergone an extensive radiation and occupy a variety of biomes.
HSV-2 infection and HPV incidence, persistence, and precancerous lesions in a cohort of HPV-vaccinated women living with HIV.
Int J STD AIDS
May 2023
Obstetrics & Gynecology, University of British Columbia, Vancouver, BC, CA.
Background: Several co-factors for HPV oncogenesis have been proposed, including co-infection with HSV-2. We assessed the relationship between HSV-2 infection and HPV-related outcomes in quadrivalent HPV-vaccinated (qHPV) women living with HIV (WLWH).
Methods: In this multi-site study of immunogenicity and efficacy of the qHPV vaccine in WLWH, visits took place at months -3, 0, 2, 6, 12, 18, 24, and annually thereafter.
The diagnosis and management of pheochromocytoma and paraganglioma during pregnancy.
Rev Endocr Metab Disord
February 2023
University of Sydney, Sydney, NSW, Australia.
Diagnosis of pheochromocytoma or paraganglioma (PPGL) in pregnancy has been associated historically with high rates of materno-fetal morbidity and mortality. Recent evidence suggests outcomes are improved by recognition of PPGL before or during pregnancy and appropriate medical management with alpha-blockade. Whether antepartum surgery (before the third trimester) is required remains controversial and open to case-based merits.
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