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Whole-Heart Histological and CMR Validation of Electroanatomic Mapping by Multielectrode Catheters in an Ovine Model.
JACC Clin Electrophysiol
January 2025
Department of Cardiology, Westmead Hospital, Sydney, New South Wales, Australia; Westmead Applied Research Centre, University of Sydney, Sydney, New South Wales, Australia. Electronic address:
Background: Accurate electroanatomic mapping is critical for identifying scar and the long-term success of ventricular tachycardia ablation.
Objectives: This study sought to determine the accuracy of multielectrode mapping (MEM) catheters to identify scar on cardiac magnetic resonance (CMR) and histopathology.
Methods: In an ovine model of myocardial infarction, we examined the effect of electrode size, spacing, and mapping rhythm on scar identification compared to CMR and histopathology using 5 multielectrode mapping catheters.
A CT-based evaluation and comparison of ganglionated plexus targeting techniques for cardioneuroablation.
Heart Rhythm
January 2025
Bordeaux University Hospital, Bordeaux, France.
Background: Cardioneuroablation (CNA) targets ganglionated plexus (GP) to treat neurally-mediated syncope, yet a standardized GP identification method is lacking. Post-processing of cardiac computed tomography (CT) identifies epicardial fat thus allowing for fat pad identification. While CT-guided CNA's feasibility is documented, data about GP anatomy and comprehensive evaluations of GP targeting methods remain scarce.
View Article and Find Full Text PDFEditorial comment on "Usefulness of peak frequency in electrograms for elimination of left atrial posterior wall residual potentials via epicardial connections".
J Arrhythm
February 2025
Department of Cardiology and Clinical Examination, Faculty of Medicine Oita University Yufu Japan.
Left atrial posterior wall (LAPW) residual potentials via epicardial connections during LAPW isolation are often low-frequency continuous potentials. Accurate annotation of these residual potentials by three-dimensional electroanatomical mapping systems is challenging and can be misleading. Herein, we present a case of successful LAPW isolation using peak frequency analysis.
View Article and Find Full Text PDFEpicardial Substrate Ablation in Symptomatic Brugada Syndrome Patients: An Updated Systematic Review and Single-arm Meta-analysis.
Heart Rhythm
January 2025
Dante Pazzanese Institute of Cardiology, Department of Electrophysiology, São Paulo, Brazil.
Background: Brugada syndrome (BrS) is a genetic heart disease that predisposes individuals to ventricular arrhythmias and sudden cardiac death. Although implantable cardioverter-defibrillators (ICDs) and quinidine are primary treatments, recurrent BrS-triggered ventricular arrhythmias can persist. In this setting, epicardial substrate ablation has emerged as a promising alternative for symptomatic patients.
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