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Beyond Classification: A Unique Case of Self-Resolving Cutaneous Mucinosis Associated With Streptococcal Infection in a Child.
Pediatr Dermatol
December 2024
Division of Dermatology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
A 3-year-old boy presented with an unusual combination of indurated skin, sclerotic plaques with lichenification, and yellowish papules. Histopathology revealed diffuse dermal mucin deposits, and laboratory tests showed a positive throat culture for Group A streptococcus and elevated serum anti-streptolysin titers. An 10-day course of oral amoxicillin was associated with near-complete resolution of all dermatological findings within 4 months.
View Article and Find Full Text PDFTo ASLO or Not to ASLO: Utility of the ASLO Test in Dermatology.
Isr Med Assoc J
April 2024
Department of Dermatology, Rambam Health Care Campus, Haifa, Israel, Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel.
Article Synopsis
- Group A Streptococcus (GAS) infections can lead to various skin diseases, and diagnosing such conditions often involves checking for signs of prior GAS infections using ASLO tests.
- A study of 152 patients who underwent ASLO testing revealed that 29% tested positive, with psoriasis and erythema nodosum showing the highest correlation with positive ASLO results.
- The findings suggest that while it's unclear how ASLO applies to all skin diseases, it may be particularly useful in diagnosing psoriasis, as all subtypes of psoriasis presented with positive ASLO results.
Atopy Does Not Influence the Clinical Outcome of Acute Urticaria: A Retrospective Study.
Int Arch Allergy Immunol
January 2024
Department of Dermatology, Southwest Hospital, Amy Medical University, Chongqing, China.
Background: Acute urticaria (AU) may be associated with atopy, but the relationship between atopic status and the clinical features of the disease has not been fully described.
Objectives: The aim of the study was to determine the proportion of atopy in AU patients and to see whether atopy is related to the clinical characteristics of AU and whether it has an impact on the outcome of the disease.
Materials And Method: A retrospective analysis of patients with AU was performed.
Long-term presence of autoantibodies in plasma of cured leprosy patients.
Sci Rep
January 2023
Department of Dermatology, First Affiliated Hospital of Kunming Medical University, Kunming, 650032, Yunnan, China.
Autoantibodies have been detected in leprosy patients, indicating that infection with M. leprae may lead to autoimmune disorders. However, whether autoimmune response last until patients are cured is unknown.
View Article and Find Full Text PDFRole of streptococcal infection in the etiopathogenesis of pityriasis lichenoides chronica and the therapeutic efficacy of azithromycin: a randomized controlled trial.
Arch Dermatol Res
April 2023
Dermatology Department, Kasr Alainy Faculty of Medicine, Cairo University, Kasr Al Ainy St, Cairo, 11562, Egypt.
The exact aetiology of pityriasis lichenoides chronica (PLC) remains unknown. While phototherapy is the most investigated therapeutic modality, azithromycin has been used scarcely. The aim of this study is to evaluate the therapeutic efficacy of azithromycin in the treatment of PLC compared to NB-UVB and evaluating the presence of streptococcal infection as a possible etiological factor in PLC patients.
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