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Augmented silver sulfadiazine nanostructured lipid carriers impregnated collagen sponge for promoting burn wound healing.
Int J Biol Macromol
January 2025
Department of Pharmaceutics, Faculty of Pharmacy, University of Sadat City, P.O. Box 32897, Menoufia, Egypt; Nanomedicine Laboratory, Faculty of Pharmacy, University of Sadat City, P.O. Box 32897, Sadat City, Egypt. Electronic address:
Silver sulfadiazine (SSD) is a widely used antibacterial agent for burn wound treatment owing to its capability in re-epithelialization and wound healing. However, due to its low solubility, the need for an effective drug delivery system is mandatory. This study aimed to optimize SSD nanostructured lipid-based carriers (NLCs), incorporated in a collagen sponge form as an innovative topical dosage form for effective burn wound treatment.
View Article and Find Full Text PDFTensor networks enable the calculation of turbulence probability distributions.
Sci Adv
January 2025
Sibley School of Mechanical and Aerospace Engineering, Cornell University, Ithaca, NY 14853, USA.
Predicting the dynamics of turbulent fluids has been an elusive goal for centuries. Even with modern computers, anything beyond the simplest turbulent flows is too chaotic and multiscaled to be directly simulatable. An alternative is to treat turbulence probabilistically, viewing flow properties as random variables distributed according to joint probability density functions (PDFs).
View Article and Find Full Text PDFThe misalignment between the geometric and optical axes, combined with rotational asymmetry, poses significant challenges for achieving high-accuracy measurement of the off-axis aspheric mirror during the fabrication and polishing processes. To address this issue, this paper presents a method based on stereo deflectometry for measuring the figure of the off-axis aspheric mirror. In this method, point cloud of the off-axis aspheric mirror is first obtained using stereo deflectometry.
View Article and Find Full Text PDFPosterior instrumented correction and fusion of Scheuermann´s results in physiological reconstruction of sagittal alignment and excellent overall clinical outcome- clinical trail of 73 patients.
BMC Musculoskelet Disord
January 2025
Department of Spine Surgery, Ameos Clinic Eutin, Eutin, Germany.
Purpose: The aim was to assess the clinical outcomes after posterior spinal fusion (PSF) in patients with Scheuermann's disease (SD).
Methods: SD undergoing PSF were retrospectively analyzed. Clinical outcome was determined using SRS-22- and Eq.
Research on calculation of transverse bending moment of deck of box girder with long-span and long cantilever.
Sci Rep
January 2025
School of Civil Engineering, Lanzhou Jiaotong University, Lanzhou, 730070, China.
To investigate the reasonable calculation value of the transverse design bending moment of a long-span cantilever box girder bridge deck under vehicle load, the plate beam model and beam element frame model were established according to the concept of load effective distribution width in the Chinese highway specifications. The local finite element model and full bridge model of a long-cantilever plate were established using the plate-shell element. The practical calculation formula and finite element analysis of the transverse bending moment of a bridge deck were studied.
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