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Evaluation of the antibacterial and antibiofilm effect of mycosynthesized silver and selenium nanoparticles and their synergistic effect with antibiotics on nosocomial bacteria.
Microb Cell Fact
January 2025
Microbiology and Immunology Department, Faculty of Medicine, Sohag University, Sohag, Egypt.
Background: The healthcare sector faces a growing threat from the rise of highly resistant microorganisms, particularly Methicillin-resistant Staphylococcus aureus (MRSA) and multidrug-resistant Pseudomonas aeruginosa (MDR P. aeruginosa). Facing the challenge of antibiotic resistance, nanoparticles have surfaced as promising substitutes for antimicrobial therapy.
View Article and Find Full Text PDFBacterial isolates and drug susceptibility patterns in infected lesions of cutaneous leishmaniasis patients at ALERT hospital, Addis Ababa, Ethiopia.
BMC Infect Dis
January 2025
Department of Medical Laboratory Sciences, College of Health Sciences, Addis Ababa University, Addis Ababa, P.O. Box 9086, Addis Ababa, Ethiopia.
Bacterial infections commonly complicate cutaneous leishmaniasis (CL), worsening the disease and delaying healing. Despite this, there is a gap in research concerning the characteristics of pathogenic microorganisms associated in CL patients. This study aims to identify bacterial isolates and drug susceptibility patterns in CL patients.
View Article and Find Full Text PDFTherapeutic potential of Chromolaena odorata, Vernonia amygdalina, and Cymbopogon citratus against pathogenic Bacteria.
Sci Rep
January 2025
Departmment of Microbiology and Immunology, Kampala International University, Ishaka, Uganda.
Antimicrobial resistance poses a global public health threat, compelling the search for alternative treatments, especially in resource-limited settings. The increasing ineffectiveness of traditional antibiotics has intensified the need to explore medicinal plants as viable therapeutic options. This study sought to compare the efficacy of certain medicinal plants used in Owerri, Nigeria, for treating pathogenic bacteria against traditional commercial antibiotics.
View Article and Find Full Text PDFevaluation of anti-microbial efficacy of and its constituents on oral biofilms.
J Indian Soc Periodontol
December 2024
Department of Periodontics, Dr. Harvansh Singh Judge Institute of Dental Sciences and Hospital, Panjab University, Chandigarh, India.
Article Synopsis
- The study investigated the antimicrobial properties of fenugreek extracts from leaves and seeds, focusing on their effectiveness against oral pathogens compared to the commonly used antiseptic chlorhexidine (CHX).
- The research utilized various methods including minimal inhibitory concentration and confocal laser scanning microscopy to assess the antimicrobial efficacy of specific fenugreek compounds (FA, DIO, and FU) against multiple bacterial strains.
- Results indicated that fenugreek extracts exhibited significant antimicrobial activity similar to CHX, suggesting they could serve as effective herbal alternatives for managing oral and periodontal infections.
Presence of qnr and aac(6́)-Ib-cr Genes among Quinolone Resistant Proteus species Isolates at Mymensingh, Bangladesh.
Mymensingh Med J
January 2025
Dr Parvez Arafa, Lecturer, Department of Virology, Mymensingh Medical College (MMC), Mymensingh, Bangladesh; E-mail:
Article Synopsis
- Fluroquinolone resistance in Enterobacteriaceae, including Proteus, poses a significant public health threat, particularly affecting treatments for UTIs and intra-abdominal infections.
- The study aimed to identify specific quinolone resistance genes in ciprofloxacin-resistant Proteus species within a defined timeframe and location in Bangladesh.
- Results showed a high prevalence (64.58%) of plasmid-mediated quinolone resistance genes among resistant isolates, indicating a concerning trend that could lead to increased resistance and transmission due to over-prescription of fluoroquinolones.
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