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The infectious allergy plays an important role in the pathogenesis of brucellosis. In the allergy diagnostic of toxoplasmosis the cell reactions in vivo are equally applied with the Burnet intradermal allergic test. In the present study the reaction of leukolysis was applied to detect the sensibilization of leucocytes in blood and saliva under brucellosis.

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The effect of intestinal helminthes (IH) and Toxoplasma gondii (Tox) co-infection on anti-mycobacterium tuberculosis (MTB) immunity in patients with active pulmonary tuberculosis was studied in 96 patients of 4 groups. Thirteen patients had TB+IH+Tox (G1), 15 had TB+IH (G2), 21 had TB+Tox (G3) and 47 had TB (G4). The mean diameter of tuberculin and toxoplasmin tests was measured to assess cell mediated immunity.

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Toxoplasmic lymphadenitis--clinical and serologic profile.

Clin Microbiol Infect

July 2003

German Hospital, Buenos Aires, Argentina.

Objective: To study the serologic profile of several types of test for toxoplasmosis, in order to contribute to the interpretation of antibody kinetics.

Methods: The clinical and serologic features of 120 cases of lymphadenopathy with known time of clinical onset were studied during 18 months postinfection. Antibody kinetics was determined by Sabin-Feldman dye test, complement fixation with light antigen, IgM immunofluorescent antibody test, and IgM immunosorbent agglutination assay (IgM-ISAGA).

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Intracutaneous test (ICT) with toxoplasmin is a technically simple and inexpensive method of laboratory diagnosis of toxoplasmosis. Of the 5472 examined sick persons, 54.28 percent displayed a positive ICT.

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A screening investigation was conducted designed to identify ill persons presenting with toxoplasmosis with the aid of an intracutaneous test with toxoplasmin and complement-fixing reaction with a dry toxoplasmic antigen. Toxoplasmosis was detected in those persons having lymphadenitis, therapeutical patients, women with aggravated obstetrical history having had spontaneous abortions and having given birth to sick children, patients with sluggish meningoencephalitis presenting with epileptoid and hypothalamic syndrome, polyneuritis, and patients with myopia, chorioretinitis and uveitis. Identification and treatment of toxoplasmic invasion constitutes a valid method of control of spontaneous abortions of toxoplasmic etiology.

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