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Multimodal bioimaging is beneficial for clinical diagnosis and research due to the provision of comprehensive diagnostic information. However, the design of multifunctional bio-probes aggregating multiple bioimaging functions is greatly challenging. In this study, a multifunctional bio-probe based on lanthanide-based nanomaterials SrGdF: Yb/Er/Tm(abbreviated as SGF) was developed formultimodal imaging by co-adopting apropos lanthanides and tuning their molar ratio.

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Article Synopsis
  • The study aims to establish clinical normative data for ulna length in children aged 1 day to 18 years across India, measuring various factors including age, sex, BMI, and hand dominance.
  • A total of 1,300 healthy children were analyzed, showing gradual ulna lengthening as they age, with significant differences in males at certain ages and a notable increase in length among obese children.
  • The findings indicate that age, gender, and geographical location influenced ulna length, but factors like BMI and hand dominance were not significant after maturity, providing valuable data for pediatric healthcare.
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The rapid increase in the worldwide prevalence of obesity and certain non-communicable diseases (NCDs), such as: cardiovascular diseases, cancers, chronic respiratory diseases, and diabetes, has been mainly attributed to an excess of sugar consumption. Although the potential benefits of the synergetic use of sweeteners have been known for many years, recent development based on synthesis strategies to produce sucrose-like taste profiles is emerging where biocatalyst approaches may be preferred to produce and supply specific sweetener compounds. From a nutritional standpoint, high-intensity sweeteners have fewer calories than sugars while providing a major sweet potency, placing them in the spotlight as valuable alternatives to sugar.

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The need of the hour with respect to cancer treatment is a targeted approach with minimal or nil ramifications. Apropos, magnetic fluid hyperthermia (MFH) is emerging as a potential therapeutic strategy with anticipated reduced side effects for solid tumors. MFH causes cytotoxicity due to the heat generated owing to Hysteresis, Neel, and Brownian relaxation losses once magnetic nanoparticles (MNPs) carrying cancer cells are placed under an alternating magnetic field.

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Purpose: Both venous and arterial thrombotic events (VTE/AT) can be associated with Immune Checkpoint Inhibitors (ICI). However, there is a paucity of information apropos patients in routine clinical practice.

Methods: /Patients.

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