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The involvements of intracellular basal calcium and membrane potential in para-phenylenediamine-impaired sperm function.
Transl Androl Urol
December 2024
Center for Reproductive Medicine, Affiliated Hospital of Nantong University, Nantong, China.
Background: Para-phenylenediamine (PPD) is a crystalline solid that belongs to the aromatic amine group, widely used in the manufacturing of various dyes. PPD exhibits toxic effects on female hormone stability, ovarian function, and embryo development. Although studies have shown that PPD exposure can damage oocyte quality in female mice, research on its effects on male reproductive capability, particularly on human sperm quality and function, is limited.
View Article and Find Full Text PDFClosing the Gap: Digital Innovations to Address Hypertension Disparities.
Curr Cardiol Rep
January 2025
Section of Cardiovascular Medicine, Yale School of Medicine, New Haven, CT, USA.
Purpose Of Review: Significant inequities persist in hypertension detection and control, with minoritized populations disproportionately experiencing organ damage and premature death due to uncontrolled hypertension. Remote blood pressure monitoring combined with telehealth visits (RBPM) is proving to be an effective strategy for controlling hypertension. Yet there are challenges related to technology adoption, patient engagement and social determinants of health (SDoH), contributing to disparities in patient outcomes.
View Article and Find Full Text PDFSexual education around the world: in Australia and Oceania and Europe.
Ginekol Pol
January 2025
Chair and Clinical Department of Gynecology, Obstetrics and Gynecological Oncology, Medical University of Silesia, Katowice, Poland, ul. Poniatowskiego 15, 40-055 Katowice, Poland.
Sexual education is a vital process of teaching and learning about various aspects of human sexuality, including physical, emotional, social, and cultural dimensions. Its primary goal is to equip individuals, especially adolescents, with the necessary knowledge, skills, and values to make informed, responsible, and safe decisions regarding their sexual and reproductive lives. This article examines sexual education programs in Australia, Oceania, and Europe, addressing the current state, the unique challenges, and recommendations for enhancing these programs to meet the needs of modern society.
View Article and Find Full Text PDFStandardizing decellularization protocols for optimized uterine tissue bioengineering.
Regen Ther
March 2025
Laboratory for Transplantation and Regenerative Medicine, Sahlgrenska Academy, University of Gothenburg, Kvinnokliniken, Blå stråket 6, 40530 Gothenburg, Sweden.
Bioengineering is applied in different areas, including women's infertility management. Among other approaches, decellularized tissues are being used to treat uterine disorders causing infertility. Biomaterials made from decellularized tissue consist of tissue-specific extracellular matrix and, as acellular scaffolds, are thought to be immune inert.
View Article and Find Full Text PDFAllergen immunotherapy in Italy: How, when, and why-A real-world study conducted through a patient association.
World Allergy Organ J
January 2025
Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, MI, Italy.
Background: Allergen immunotherapy (AIT) is the only treatment that modifies the natural course of allergies. However, AIT is only used in some eligible patients, is frequently underused, and only a few studies investigated this aspects. Understanding AIT utilization patterns might disclose information about why it is underused, thus providing valuable insights on how to broaden the positive impact it can have on the population.
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